Rabbit anti-Human ELOVL2 Polyclonal Antibody | anti-ELOVL2 antibody

ELOVL2 Antibody

Cat. Num. AAA7004683

• Gene Names: ELOVL2; SSC2
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry, Immunofluorescence
• Purity: >95%,Protein G purified
• Synonyms: ELOVL2; Polyclonal Antibody; ELOVL2 Antibody; Elongation of very long chain fatty acids protein 2; 3-keto acyl-CoA synthase ELOVL2; ELOVL fatty acid elongase 2; ELOVL FA elongase 2; Very-long-chain 3-oxoacyl-CoA synthase 2; SSC2; anti-ELOVL2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%,Protein G purified
• Form/Format: Liquid
• Sequence Length: 296

• Applicable Applications for anti-ELOVL2 antibody: ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Immunogen: Recombinant human Elongation of very long chain fatty acids protein 2 protein
• Conjugation: Non-conjugated
• Storage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-54872 / sc-54874
• Preparation and Storage: Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver cancer using MBS7004683 at dilution of 1:100)

Immunofluorescence (IF)

(Immunofluorescent analysis of HepG2 cells using MBS7004683 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Related Product Information for anti-ELOVL2 antibody

Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.

NCBI and Uniprot Product Information

• NCBI GI #: 157388945
• NCBI GeneID: 54898
• NCBI Accession #: NP_060240.3
• NCBI GenBank Nucleotide #: NM_017770.3
• UniProt Accession #: Q9NXB9; Q6P9E1; Q86W94
• Molecular Weight: 34,585 Da
• NCBI Official Full Name: elongation of very long chain fatty acids protein 2
• NCBI Official Synonym Full Names: ELOVL fatty acid elongase 2
• NCBI Official Symbol: ELOVL2
• NCBI Official Synonym Symbols: SSC2
• NCBI Protein Information: elongation of very long chain fatty acids protein 2
• UniProt Protein Name: Elongation of very long chain fatty acids protein 2
• Protein Family: Elongation of very long chain fatty acids protein
• UniProt Gene Name: ELOVL2
• UniProt Synonym Gene Names: ELOVL FA elongase 2
• UniProt Entry Name: ELOV2_HUMAN

Uniprot Description

ELOVL2: Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Belongs to the ELO family.

Protein type: Membrane protein, integral; Lipid Metabolism - unsaturated fatty acid biosynthesis; EC 2.3.1.199; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6p24.2

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane

Molecular Function: fatty acid elongase activity; protein binding

Biological Process: cellular lipid metabolic process; linoleic acid metabolic process; triacylglycerol biosynthetic process; unsaturated fatty acid biosynthetic process; unsaturated fatty acid metabolic process; very-long-chain fatty acid biosynthetic process