Western Blot (WB)
(Western Blot analysis of Rat brain membrane lysate showing detection of VAChT protein using Mouse Anti-VAChT Monoclonal Antibody, Clone S6-38. Primary Antibody: Mouse Anti-VAChT Monoclonal Antibody at 1:1000.)
Mouse VAChT Monoclonal Antibody | anti-SLC18A3 antibody
VAChT Antibody: Alkaline Phosphatase
Western Blot (WB)
(Western Blot analysis of Rat brain membrane lysate showing detection of VAChT protein using Mouse Anti-VAChT Monoclonal Antibody, Clone S6-38. Primary Antibody: Mouse Anti-VAChT Monoclonal Antibody at 1:1000.)
Western Blot (WB)
(Western Blot analysis of Rat brain membrane lysate showing detection of VAChT protein using Mouse Anti-VAChT Monoclonal Antibody, Clone S6-38. Primary Antibody: Mouse Anti-VAChT Monoclonal Antibody at 1:1000.)
Scientific Background: VAChT is a member of the vesicular amine transporter (VMAT) family. The encoded transmembrane protein transports acetylcholine into secretory vesicle for release into the extracellular space. Acetylcholine (Ach) transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene.
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene. [provided by RefSeq, Jul 2008]
Uniprot Description
SLC18A3: Involved in acetylcholine transport into synaptic vesicles. Belongs to the major facilitator superfamily. Vesicular transporter family.
Protein type: Membrane protein, integral; Transporter; Membrane protein, multi-pass; Transporter, SLC family
Chromosomal Location of Human Ortholog: 10q11.2
Cellular Component: membrane; integral to plasma membrane; plasma membrane
Molecular Function: acetylcholine transmembrane transporter activity
Biological Process: synaptic transmission; acetylcholine transport; neurotransmitter secretion
Research Articles on SLC18A3
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Product Notes
The SLC18A3 slc18a3 (Catalog #AAA802633) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The VAChT Antibody: Alkaline Phosphatase reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's VAChT can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). 1:50-1:200 (IHC). Researchers should empirically determine the suitability of the SLC18A3 slc18a3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VAChT, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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