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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver using MBS768994 (Endostatin, COL18A1 antibody) at dilution of 1:50)

Rabbit anti-Human Endostatin Polyclonal Antibody | anti-Col18a1 antibody

Endostatin Rabbit Polyclonal

Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
Endostatin; Polyclonal Antibody; Endostatin Rabbit Polyclonal; anti-Col18a1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
184
Applicable Applications for anti-Col18a1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen
Collagen, type XVIII, alpha 1
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver using MBS768994 (Endostatin, COL18A1 antibody) at dilution of 1:50)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver using MBS768994 (Endostatin, COL18A1 antibody) at dilution of 1:50)

Western Blot (WB)

(human liver tissue were subjected to SDS PAGE followed by western blot with MBS768994 (Endostatin, COL18A1 antibody) at dilution of 1:500)

Western Blot (WB) (human liver tissue were subjected to SDS PAGE followed by western blot with MBS768994 (Endostatin, COL18A1 antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
134,204 Da
NCBI Official Full Name
endostatin, partial
NCBI Official Synonym Full Names
collagen, type XVIII, alpha 1
NCBI Official Symbol
Col18a1
NCBI Protein Information
collagen alpha-1(XVIII) chain
UniProt Protein Name
Collagen alpha-1(XVIII) chain
Protein Family
UniProt Gene Name
Col18a1
UniProt Entry Name
COIA1_MOUSE

Uniprot Description

COL18A1: COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube. Defects in COL18A1 are a cause of Knobloch syndrome type 1 (KNO1). An autosomal recessive disorder defined by the occurrence of high myopia, vitreoretinal degeneration with retinal detachment, macular abnormalities and occipital encephalocele. Belongs to the multiplexin collagen family. 3 isoforms of the human protein are produced by alternative promoter.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: basement membrane; collagen; extracellular matrix; extracellular region; extracellular space; proteinaceous extracellular matrix

Molecular Function: identical protein binding; metal ion binding; structural molecule activity

Biological Process: angiogenesis; cell adhesion; endothelial cell morphogenesis; extracellular matrix organization and biogenesis; positive regulation of cell migration; positive regulation of cell proliferation

Research Articles on Col18a1

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Product Notes

The Col18a1 col18a1 (Catalog #AAA768994) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Endostatin Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Endostatin can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the Col18a1 col18a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Endostatin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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