Rabbit anti-Human ARID4B Polyclonal Antibody | anti-ARID4B antibody

ARID4B Rabbit Polyclonal

Cat. Num. AAA766799

• Gene Names: ARID4B; BCAA; BRCAA1; RBP1L1; SAP180; RBBP1L1
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunofluorescence, Immunohistochemistry, Immunoprecipitation
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: ARID4B; Polyclonal Antibody; ARID4B Rabbit Polyclonal; anti-ARID4B antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 1312

• Applicable Applications for anti-ARID4B antibody: ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP)
• Immunogen: AT rich interactive domain 4B (RBP1-like)
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis tissue slide using MBS766799 (ARID4B Antibody) at dilution of 1:50)

Testing Data

()

Western Blot (WB)

(MCF-7 cells were subjected to SDS PAGE followed by western blot with MBS766799 (ARID4B Antibody) at dilution of 1:600)

NCBI and Uniprot Product Information

• NCBI GI #: 332164768
• NCBI GeneID: 51742
• NCBI Accession #: NP_001193723.1
• NCBI GenBank Nucleotide #: NM_001206794.1
• Molecular Weight: 91,140 Da
• NCBI Official Full Name: AT-rich interactive domain-containing protein 4B isoform 1
• NCBI Official Synonym Full Names: AT-rich interaction domain 4B
• NCBI Official Symbol: ARID4B
• NCBI Official Synonym Symbols: BCAA; BRCAA1; RBP1L1; SAP180; RBBP1L1
• NCBI Protein Information: AT-rich interactive domain-containing protein 4B
• UniProt Protein Name: AT-rich interactive domain-containing protein 4B
• Protein Family: AT-rich interactive domain-containing protein
• UniProt Gene Name: ARID4B
• UniProt Synonym Gene Names: BRCAA1; RBBP1L1; RBP1L1; SAP180; ARID domain-containing protein 4B; Sin3-associated polypeptide p180
• UniProt Entry Name: ARI4B_HUMAN

NCBI Description

This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]

Uniprot Description

ARID4B: Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 1q42.3

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function: histone deacetylase activity; protein binding

Biological Process: genetic imprinting; histone deacetylation; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; spermatogenesis; transcription, DNA-dependent