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Western Blot (WB) (Western blot analysis BRCAA1 using HuvEc whole cell lysates)

Rabbit BRCAA1 Polyclonal Antibody | anti-BRCAA1 antibody

BRCAA1 Antibody

Gene Names
ARID4B; BCAA; BRCAA1; RBP1L1; SAP180; RBBP1L1
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Synonyms
BRCAA1; Polyclonal Antibody; BRCAA1 Antibody; ARID4B; SIN3A-associated protein 180; BCAA; Rb-binding protein homolog; RBBP1L1; RBP1L1; SAP180; anti-BRCAA1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
BRCAA1 Antibody detects endogenous levels of total BRCAA1
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (varies by lot)
Sequence Length
1312
Applicable Applications for anti-BRCAA1 antibody
Western Blot (WB)
Application Notes
Western Blot: 1:1000-3000
Immunogen
A synthesized peptide derived from human BRCAA1
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis BRCAA1 using HuvEc whole cell lysates)

Western Blot (WB) (Western blot analysis BRCAA1 using HuvEc whole cell lysates)
Product Categories/Family for anti-BRCAA1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
91,140 Da
NCBI Official Full Name
AT-rich interactive domain-containing protein 4B isoform 1
NCBI Official Synonym Full Names
AT-rich interaction domain 4B
NCBI Official Symbol
ARID4B
NCBI Official Synonym Symbols
BCAA; BRCAA1; RBP1L1; SAP180; RBBP1L1
NCBI Protein Information
AT-rich interactive domain-containing protein 4B
UniProt Protein Name
AT-rich interactive domain-containing protein 4B
UniProt Gene Name
ARID4B
UniProt Synonym Gene Names
BRCAA1; RBBP1L1; RBP1L1; SAP180; ARID domain-containing protein 4B; Sin3-associated polypeptide p180
UniProt Entry Name
ARI4B_HUMAN

NCBI Description

This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]

Uniprot Description

ARID4B: Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 1q42.3

Cellular Component: nucleoplasm; nucleus

Molecular Function: histone deacetylase activity; protein binding

Biological Process: regulation of transcription from RNA polymerase II promoter

Research Articles on BRCAA1

Similar Products

Product Notes

The BRCAA1 arid4b (Catalog #AAA9418712) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BRCAA1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's BRCAA1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:1000-3000. Researchers should empirically determine the suitability of the BRCAA1 arid4b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BRCAA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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