Guinea Pig Ankyrin repeat domain-containing protein 11 (ANKRD11) ELISA Kit | ANKRD11 elisa kit
Guinea pig Ankyrin repeat domain-containing protein 11 (ANKRD11) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This locus encodes an ankryin repeat domain-containing protein. The encoded protein inhibits ligand-dependent activation of transcription. Mutations in this gene have been associated with KBG syndrome, which is characterized by macrodontia, distinctive craniofacial features, short stature, skeletal anomalies, global developmental delay, seizures and intellectual disability. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 2 and X. [provided by RefSeq, Jan 2012]
Uniprot Description
ANKRD11: May recruit HDACs to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation. Defects in ANKRD11 are the cause of KBG syndrome (KBGS). A syndrome characterized by macrodontia of the upper central incisors, distinctive craniofacial findings, short stature, skeletal anomalies, and neurologic involvement that includes global developmental delay, seizures, and intellectual disability.
Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 16q24.3
Cellular Component: nucleoplasm; cytoplasm; plasma membrane; nucleus
Biological Process: skeletal morphogenesis; in utero embryonic development; multicellular organism growth; tissue homeostasis; odontogenesis of dentine-containing teeth
Disease: Kbg Syndrome
Research Articles on ANKRD11
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Product Notes
The Guinea Pig ANKRD11 ankrd11 (Catalog #AAA7251518) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7251518 ELISA Kit recognizes Guinea Pig ANKRD11. It is sometimes possible for the material contained within the vial of "Ankyrin repeat domain-containing protein 11 (ANKRD11), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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