Pyruvate kinase muscle isozyme (PKM2) Recombinant Protein | PKM2 recombinant protein
Recombinant Chicken Pyruvate kinase muscle isozyme (PKM2), partial
Gene Names
PKM; PKLR; PKM2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Pyruvate kinase muscle isozyme (PKM2); Recombinant Chicken Pyruvate kinase muscle isozyme (PKM2); partial; PKM2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-530. Full Length of Mature Protein
Sequence
SKHHDAGTAFIQTQQLHAAMADTFLEHMCRLDIDSEPTIARNTGIICTIGPASRSVDKLKEMIKSGMNVARLNFSHGTHEYHEGTIKNVREATESFASDPITYRPVAIALDTKGPEIRTGLIKGSGTAEVELKKGAALKVTLDNAFMENCDENVLWVDYKNLIKVIDVGSKIYVDDGLISLLVKEKGKDFVMTEVENGGMLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQNVDMVFASFIRKAADVHAVRKVLGEKGKHIKIISKIENHEGVRRFDEIMEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPIICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHAIAREAEAAMFHRQQFEEILRHSVHHREPADAMAAGAVEASFKCLAAALIVMTESGRSAHLVSRYRPRAPIIAVTRNDQTARQAHLYRGVFPVLCKQPAHDAWAEDVDLRVNLGMNVGKARGFFKTGDLVIVLTGWRPGSGYTNTMRVVPVP
Species
Chicken
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for PKM2 recombinant protein
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
58,015 Da
NCBI Official Full Name
pyruvate kinase PKM
NCBI Official Synonym Full Names
pyruvate kinase, muscle
NCBI Official Symbol
PKM
NCBI Official Synonym Symbols
PKLR; PKM2
NCBI Protein Information
pyruvate kinase PKM
UniProt Protein Name
Pyruvate kinase PKM
UniProt Gene Name
PKM
Uniprot Description
Plays a key role in glycolysis.
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Product Notes
The PKM2 pkm (Catalog #AAA718750) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-530. Full Length of Mature Protein. The amino acid sequence is listed below: SKHHDAGTAF IQTQQLHAAM ADTFLEHMCR LDIDSEPTIA RNTGIICTIG PASRSVDKLK EMIKSGMNVA RLNFSHGTHE YHEGTIKNVR EATESFASDP ITYRPVAIAL DTKGPEIRTG LIKGSGTAEV ELKKGAALKV TLDNAFMENC DENVLWVDYK NLIKVIDVGS KIYVDDGLIS LLVKEKGKDF VMTEVENGGM LGSKKGVNLP GAAVDLPAVS EKDIQDLKFG VEQNVDMVFA SFIRKAADVH AVRKVLGEKG KHIKIISKIE NHEGVRRFDE IMEASDGIMV ARGDLGIEIP AEKVFLAQKM MIGRCNRAGK PIICATQMLE SMIKKPRPTR AEGSDVANAV LDGADCIMLS GETAKGDYPL EAVRMQHAIA REAEAAMFHR QQFEEILRHS VHHREPADAM AAGAVEASFK CLAAALIVMT ESGRSAHLVS RYRPRAPIIA VTRNDQTARQ AHLYRGVFPV LCKQPAHDAW AEDVDLRVNL GMNVGKARGF FKTGDLVIVL TGWRPGSGYT NTMRVVPVP . It is sometimes possible for the material contained within the vial of "Pyruvate kinase muscle isozyme (PKM2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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