Tumor Associated Calcium Signal Transducer 2 Recombinant Protein | TACSTD2 recombinant protein

Recombinant Tumor Associated Calcium Signal Transducer 2 (TACSTD2)

Cat. Num. AAA2032980

• Gene Names: Tacstd2; Ly97; EGP-1; TROP2; C80403; GA733-1
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 95%
• Synonyms: Tumor Associated Calcium Signal Transducer 2; Recombinant Tumor Associated Calcium Signal Transducer 2 (TACSTD2); EGP-1; M1S1; TROP2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1; Cell surface glycoprotein Trop-2; TACSTD2 recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
• Sequence: RVVRVPAGT LVRVVGTELV IPCNVSDYDG PSEQNFDWSF SSSGSSFVEL ASTWEVGFPA QLYRERLQRG DILLRRTAND AVELHIKNVQ PSDQGHYKCS TPSTDATVQG NYEDTVQVKV LADALVVGPS SRPPPGLSLR EGEPFELRCI ASTTSPLHTH LALRWELHRG PVHRSILALS HEGRFHPGPG YEQRYHSGDV RLDTVGSDAY RLSVARALSA DQGSYRCVVSEWITEQGSWQ EIQ
• Sequence Length: 317

• Applicable Applications for TACSTD2 recombinant protein: SDS-PAGE, Western (WB), ELISA (EIA), Immunoprecipitation (IP).
• Predicted Molecular Mass: 30.5kDa
• Usage: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Endotoxin Level: <1.0EU per 1 ug (determined by the LAL method)
• Expression System: Prokaryotic expression
• Fragment: Arg22~Gln263
• Organism Species: Mouse
• Tag: two N-terminal Tags, His-tag and T7-tag
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 31560359
• NCBI GeneID: 56753
• NCBI Accession #: NP_064431.2
• NCBI GenBank Nucleotide #: NM_020047.3
• Molecular Weight: 35,574 Da
• NCBI Official Full Name: tumor-associated calcium signal transducer 2
• NCBI Official Synonym Full Names: tumor-associated calcium signal transducer 2
• NCBI Official Symbol: Tacstd2
• NCBI Official Synonym Symbols: Ly97; EGP-1; TROP2; C80403; GA733-1
• NCBI Protein Information: tumor-associated calcium signal transducer 2
• UniProt Protein Name: Tumor-associated calcium signal transducer 2
• Protein Family: Tumor-associated calcium signal transducer
• UniProt Gene Name: Tacstd2
• UniProt Synonym Gene Names: Trop2
• UniProt Entry Name: TACD2_MOUSE

Uniprot Description

TACSTD2: May function as a growth factor receptor. Defects in TACSTD2 are the cause of gelatinous drop-like corneal dystrophy (GDLD); also known as lattice corneal dystrophy type III. GDLD is an autosomal recessive disorder characterized by grayish corneal amyloid deposits that cause severe visual impairment. Belongs to the EPCAM family.

Protein type: Membrane protein, integral; Receptor, misc.

Cellular Component: basal plasma membrane; extracellular space; integral to membrane; lateral plasma membrane; membrane; nucleus; plasma membrane

Biological Process: negative regulation of stress fiber formation