Rabbit anti-Human, Mouse TFF1 Polyclonal Antibody | anti-TFF1 antibody

TFF1 Antibody

Cat. Num. AAA7124360

• Gene Names: TFF1; pS2; BCEI; HPS2; HP1.A; pNR-2; D21S21
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Antigen Affinity Purification
• Synonyms: TFF1; Polyclonal Antibody; TFF1 Antibody; Trefoil factor 1; anti-TFF1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purification
• Form/Format: Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol

• Applicable Applications for anti-TFF1 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: ELISA: 1:2000-1:5000; WB: 1:500-1:2000; IHC: 1:25-1:100
• Immunogen: Fusion protein of human TFF1
• Immunogen Species: Human
• Conjugate: Non-conjugated
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using MBS7124360(TFF1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7124360(TFF1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200))

SDS-Page

(Gel: 10+12%SDS-PAGE, Lysate: 40 ug, Lane: Mouse intestinum tenue tissue, Primary antibody: MBS7124360(TFF1 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes)

Product Categories/Family for anti-TFF1 antibody

Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 4507451
• NCBI GeneID: 7031
• NCBI Accession #: NP_003216.1
• NCBI GenBank Nucleotide #: NM_003225.2
• UniProt Accession #: P04155
• Molecular Weight: 9,150 Da
• NCBI Official Full Name: trefoil factor 1
• NCBI Official Synonym Full Names: trefoil factor 1
• NCBI Official Symbol: TFF1
• NCBI Official Synonym Symbols: pS2; BCEI; HPS2; HP1.A; pNR-2; D21S21
• NCBI Protein Information: trefoil factor 1; protein pS2; polypeptide P1.A; gastrointestinal trefoil protein pS2; breast cancer estrogen-inducible protein; breast cancer estrogen-inducible sequence
• UniProt Protein Name: Trefoil factor 1
• Protein Family: Trefoil factor
• UniProt Gene Name: TFF1
• UniProt Synonym Gene Names: BCEI; PS2; hP1.A
• UniProt Entry Name: TFF1_HUMAN

NCBI Description

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]

Uniprot Description

TFF1: Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: extracellular space

Molecular Function: protein binding; growth factor activity

Biological Process: negative regulation of cell proliferation; response to peptide hormone stimulus; maintenance of gastrointestinal epithelium; digestion; carbohydrate metabolic process; cell differentiation; response to iron ion; response to estradiol stimulus