Inward rectifier potassium channel 2 (Kcnj2) Recombinant Protein | Kcnj2 recombinant protein

Recombinant Rat Inward rectifier potassium channel 2 (Kcnj2), partial

• Gene Names: Kcnj2; Kir2.1
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Inward rectifier potassium channel 2 (Kcnj2); Recombinant Rat Inward rectifier potassium channel 2 (Kcnj2); partial; Kcnj2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 427

• Species: Rattus norvegicus (Rat)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 8393652
• NCBI GeneID: 29712
• NCBI Accession #: NP_058992.1
• NCBI GenBank Nucleotide #: NM_017296.1
• UniProt Accession #: Q64273
• Molecular Weight: 48,200 Da
• NCBI Official Full Name: inward rectifier potassium channel 2
• NCBI Official Synonym Full Names: potassium voltage-gated channel subfamily J member 2
• NCBI Official Symbol: Kcnj2
• NCBI Official Synonym Symbols: Kir2.1
• NCBI Protein Information: inward rectifier potassium channel 2
• UniProt Protein Name: Inward rectifier potassium channel 2
• Protein Family: Inward rectifier potassium channel
• UniProt Gene Name: Kcnj2
• UniProt Synonym Gene Names: Irk1; IRK-1; RBL-IRK1

NCBI Description

inwardly-rectifying potassium channel; involved in membrane polarization [RGD, Feb 2006]

Uniprot Description

Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium ().