Western Blot (WB)
(All lanes: Cytidine deaminase at 2ug/ml+293T whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 17 kDaObserved band size: 17 kDa)
Rabbit anti-Human Cytidine deaminase Polyclonal Antibody | anti-CDA antibody
Rabbit anti-human Cytidine deaminase polyclonal Antibody
Western Blot (WB)
(All lanes: Cytidine deaminase at 2ug/ml+293T whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 17 kDaObserved band size: 17 kDa)
Western Blot (WB)
(All lanes: Cytidine deaminase at 2ug/ml+293T whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 17 kDaObserved band size: 17 kDa)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embeded human spleen using MBS7004969 at dilution of 1:50)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embeded human spleen using MBS7004969 at dilution of 1:50)
Immunohistochemistry (IHC)
(Immunofluorescent analysis of Hela cells using MBS7004969 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Immunohistochemistry (IHC)
(Immunofluorescent analysis of Hela cells using MBS7004969 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias. [provided by RefSeq, Jul 2008]
Uniprot Description
CDA: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. Belongs to the cytidine and deoxycytidylate deaminase family.
Protein type: Xenobiotic Metabolism - drug metabolism - other enzymes; EC 3.5.4.5; Nucleotide Metabolism - pyrimidine; Hydrolase
Chromosomal Location of Human Ortholog: 1p36.2-p35
Cellular Component: cytosol; extracellular region
Molecular Function: cytidine deaminase activity; nucleoside binding; protein binding; protein homodimerization activity; zinc ion binding
Biological Process: cell surface receptor linked signal transduction; cytidine deamination; cytosine metabolic process; negative regulation of cell growth; negative regulation of nucleotide metabolic process; nucleobase, nucleoside and nucleotide metabolic process; protein homotetramerization; pyrimidine base metabolic process; pyrimidine nucleoside salvage; pyrimidine salvage
Research Articles on CDA
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Product Notes
The CDA cda (Catalog #AAA7004969) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Cytidine deaminase polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Cytidine deaminase can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Recommended dilution: WB:1:500-2000, IHC:1:20-1:200. Researchers should empirically determine the suitability of the CDA cda for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytidine deaminase, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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