Rabbit TRAPPC10 Polyclonal Antibody | anti-TRAPPC10 antibody

TRAPPC10 Polyclonal Antibody

Cat. Num. AAA3011730

• Gene Names: TRAPPC10; EHOC1; GT334; TMEM1; TRS30; EHOC-1; TRS130
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunofluorescence
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: TRAPPC10; Polyclonal Antibody; TRAPPC10 Polyclonal Antibody; Trafficking protein particle complex subunit 10; Epilepsy holoprosencephaly candidate 1 protein; EHOC-1; Protein GT334; Trafficking protein particle complex subunit; TMEM1; Transport protein particle subunit TMEM1; TRAPP subunit TMEM1; EHOC1; anti-TRAPPC10 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: TRAPPC10 polyclonal antibody detects endogenous levels of TRAPPC10 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 1259

• Applicable Applications for anti-TRAPPC10 antibody: Western Blot (WB), Immunofluorescence (IF)
• Application Notes: WB: 1:500-1:2000; IF: 1:50-1:200
• Immunogen: Recombinant full length Human TRAPPC10.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of extracts of various cell lines, using TRAPPC10 antibody.)

Immunofluorescence (IF)

(Immunofluorescence analysis of U2OS cells using TRAPPC10 antibody.)

Related Product Information for anti-TRAPPC10 antibody

TRAPPC10, also known as TMEM1 (transmembrane protein 1), EHOC1 (epilepsy holoprosencephaly candidate 1 protein) or GT334, is a widely expressed 1, 259 amino acid protein that may function in vesicular transport. Despite its name, TRAPPC10 does not contain transmembrane domains. It is the human ortholog of the yeast Trs130 protein and its structure and function appears to be conserved. Localizing to the cis-Golgi apparatus, TRAPPC10 is believed to be involved in transport from the endoplasmic reticulum (ER) to the Golgi functioning as a component of the multisubunit transport protein particle (TRAPP) complex. Mutations in the gene encoding TRAPPC10 may be involved in autoimmune polyglandular disease type 1 or Unverricht-Lundborg disease, an autosomal recessive type of progressive myoclonic epilepsy.

NCBI and Uniprot Product Information

• NCBI GI #: 48928029
• NCBI GeneID: 7109
• NCBI Accession #: NP_003265.3
• NCBI GenBank Nucleotide #: NP_003265.3
• UniProt Accession #: P48553
• Molecular Weight: ~ 112kDa
• NCBI Official Full Name: trafficking protein particle complex subunit 10 isoform a
• NCBI Official Synonym Full Names: trafficking protein particle complex 10
• NCBI Official Symbol: TRAPPC10
• NCBI Official Synonym Symbols: EHOC1; GT334; TMEM1; TRS30; EHOC-1; TRS130
• NCBI Protein Information: trafficking protein particle complex subunit 10
• UniProt Protein Name: Trafficking protein particle complex subunit 10
• Protein Family: Trafficking protein particle complex
• UniProt Gene Name: TRAPPC10
• UniProt Synonym Gene Names: EHOC1; TMEM1; EHOC-1; TRAPP subunit TMEM1
• UniProt Entry Name: TPC10_HUMAN

NCBI Description

The protein encoded by this gene is a transmembrane protein found in the cis-Golgi complex. The encoded protein is part of the multisubunit transport protein particle (TRAPP) complex and may be involved in vesicular transport from the endoplasmic reticulum to the Golgi. Mutations in this gene could be responsible for the Unverricht-Lundborg type of progressive myoclonus epilepsy, or for autoimmune polyglandular disease type 1. [provided by RefSeq, Jul 2008]