Western Blot (WB)
(Western blot analysis of lysates from HeLa cell line, mouse kidney tissue lysate (from left to right), using CDA Antibody (C-term). MBS9205681 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
Rabbit anti-Human, mouse CDA Polyclonal Antibody | anti-CDA antibody
CDA Antibody (C-term)
Western Blot (WB)
(Western blot analysis of lysates from HeLa cell line, mouse kidney tissue lysate (from left to right), using CDA Antibody (C-term). MBS9205681 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
Western Blot (WB)
(Western blot analysis of lysates from HeLa cell line, mouse kidney tissue lysate (from left to right), using CDA Antibody (C-term). MBS9205681 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
Western Blot (WB)
(Western blot analysis of anti-CDA Antibody (C-term) in mouse kidney tissue lysates (35ug/lane). CDA (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of anti-CDA Antibody (C-term) in mouse kidney tissue lysates (35ug/lane). CDA (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of anti-CDA Antibody (C-term) in Hela cell line lysates (35ug/lane). CDA (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of anti-CDA Antibody (C-term) in Hela cell line lysates (35ug/lane). CDA (arrow) was detected using the purified Pab.)
Demontis S., Terao M.Biochim. Biophys. Acta 1443:323-333(1998)
Kuhn K., Bertling W.M., Emmrich F.Biochem. Biophys. Res. Commun. 190:1-7(1993)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias. [provided by RefSeq, Jul 2008]
Uniprot Description
CDA: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. Belongs to the cytidine and deoxycytidylate deaminase family.
Protein type: Nucleotide Metabolism - pyrimidine; EC 3.5.4.5; Hydrolase; Xenobiotic Metabolism - drug metabolism - other enzymes
Chromosomal Location of Human Ortholog: 1p36.2-p35
Cellular Component: extracellular region; cytosol
Molecular Function: protein homodimerization activity; zinc ion binding; nucleoside binding; cytidine deaminase activity
Biological Process: cell surface receptor linked signal transduction; cytosine metabolic process; pyrimidine base metabolic process; nucleobase, nucleoside and nucleotide metabolic process; cytidine deamination; pyrimidine nucleoside salvage; negative regulation of cell growth; pyrimidine salvage; negative regulation of nucleotide metabolic process; protein homotetramerization
Research Articles on CDA
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Product Notes
The CDA cda (Catalog #AAA9205681) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 118-146. The CDA Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CDA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the CDA cda for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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