MDC (CCL22) Active Protein | MDC active protein
Mouse MDC (CCL22)
Gene Names
Ccl22; MDC; DCBCK; ABCD-1; Scya22
Reactivity
Mouse
Purity
> 98% (SDS-PAGE; HPLC)
Synonyms
MDC (CCL22); Mouse MDC (CCL22); Recombinant Murine MDC; MDC active protein
Host
E Coli
Reactivity
Mouse
Purity/Purification
> 98% (SDS-PAGE; HPLC)
Form/Format
Lyophilized
Sequence
GPYGANVEDS ICCQDYIRHP LPSRLVKEFF WTSKSCRKPG VVLITV KNRD ICADPRQVWV KKLLHKLS
Sequence Length
92
Endotoxin Level
< 0.1 ng/ug
Biological Activity
Determined by its ability to chemoattract human activated lymphocytes using a concentration of 10.0-100.0 ng/ml.
Related Product Information for MDC active protein
MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells and exerts HIV suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity but retains HIV suppressive activity. Recombinant murine MDC is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Product Categories/Family for MDC active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
7.8 kDa
NCBI Official Full Name
C-C motif chemokine 22
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 22
NCBI Official Symbol
Ccl22
NCBI Official Synonym Symbols
MDC; DCBCK; ABCD-1; Scya22
NCBI Protein Information
C-C motif chemokine 22; CC chemokine ABCD-1; small-inducible cytokine A22; activated B and dendritic cell-derived; small inducible cytokine subfamily A22; dendritic cell and B cell derived chemokine; small inducible cytokine subfamily A, member 22; SMALL INDUCIBLE CYTOKINE A22 PRECURSOR (CC CHEMOKINE ABCD-1) (ACTIVATED B AND DENDRITIC CELL-DERIVED)
UniProt Protein Name
C-C motif chemokine 22
UniProt Gene Name
Ccl22
UniProt Synonym Gene Names
Abcd1; Scya22
UniProt Entry Name
CCL22_MOUSE
Uniprot Description
Function: Chemotactic for activated T-lymphocytes. May play an important role in the collaboration of dendritic cells and B-lymphocytes with T-cells in immune responses.
Subcellular location: Secreted.
Tissue specificity: Expressed by activated splenic B-lymphocytes and dendritic cells. Low expression in lung, thymocytes, lymph node, and unstimulated splenic cells.
Sequence similarities: Belongs to the intercrine beta (chemokine CC) family.
Research Articles on MDC
Similar Products
Product Notes
The MDC ccl22 (Catalog #AAA692094) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Mouse MDC (CCL22) reacts with Mouse and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: GPYGANVEDS ICCQDYIRHP LPSRLVKEFF WTSKSCRKPG VVLITV KNRD ICADPRQVWV KKLLHKLS. It is sometimes possible for the material contained within the vial of "MDC (CCL22), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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