MCP-3 (CCL7) active protein
Human MCP-3 (CCL7)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq, Jul 2008]
Uniprot Description
Function: Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.
Subunit structure: Monomer. Ref.8
Subcellular location: Secreted.
Post-translational modification: O-glycosylated.
Sequence similarities: Belongs to the intercrine beta (chemokine CC) family.
Sequence caution: The sequence CAA50405.1 differs from that shown. Reason: Erroneous initiation. The sequence CAA50406.1 differs from that shown. Reason: Erroneous initiation. The sequence CAA51055.1 differs from that shown. Reason: Erroneous initiation.
Research Articles on MCP-3 (CCL7)
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Product Notes
The MCP-3 (CCL7) ccl7 (Catalog #AAA691950) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human MCP-3 (CCL7) reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: QPVGINTSTT CCYRFINKKI PKQRLESYRR TTSSHCPREA VIFKTK LDKE ICADPTQKWV QDFMKHLDKK TQTPKL. It is sometimes possible for the material contained within the vial of "MCP-3 (CCL7), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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