mGluR2,3 peptide | Grm3 peptide
mGluR2,3 peptide (Metabotropic Glutamate Receptor)
Gene Names
Grm3; mGlu3; Gprc1c; mGluR3; 0710001G23Rik
Applications
Western Blot, Immunoprecipitation, Immunocytochemistry
Purity
~95%. Purified by HPLC
Synonyms
mGluR2; 3 peptide; 3 peptide (Metabotropic Glutamate Receptor); Grm3 peptide
Purity/Purification
~95%. Purified by HPLC
Form/Format
Supplied as a lyophilized powder.
Applicable Applications for Grm3 peptide
Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)
Sequence (linear)
H-Gly-Arg-Glu-Val-Val-Asp-Ser-Thr-Thr-Ser-Ser-Leu-OH
Molecular Formula
C50H87N15O22
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Stable for 12 months at -20 degree C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for Grm3 peptide
Metabotropic glutamate receptors have been classified into three groups. In general, class I receptors (mGluR1 and mGluR5) mediate the excitation of neurons, whereas activation of class II (mGluR2 and mGluR3) and class III (mGluR4a, mGluR7a, mGluR7b and mGluR8) results in a depression of synaptic transmission. Class I mGluRs are localized in the postsynaptic membrane and are positively coupled to phospholipase C (PLC). Class II and class III mGluRs localized to the presynaptic membrane and are negatively coupled to adenylate cyclase. It has been speculated that mGluR2 and/or mGluR3 may play a role in the modulation of the mossy terminal function.
Product Categories/Family for Grm3 peptide
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
1250.34
NCBI Official Full Name
metabotropic glutamate receptor 3
NCBI Official Synonym Full Names
glutamate receptor, metabotropic 3
NCBI Official Symbol
Grm3
NCBI Official Synonym Symbols
mGlu3; Gprc1c; mGluR3; 0710001G23Rik
NCBI Protein Information
metabotropic glutamate receptor 3; G protein-coupled receptor, family C, group 1, member C
UniProt Protein Name
Metabotropic glutamate receptor 3
Protein Family
UniProt Gene Name
Grm3
UniProt Synonym Gene Names
Gprc1c; Mglur3; mGluR3
UniProt Entry Name
GRM3_MOUSE
Uniprot Description
Function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
Subunit structure: Interacts with GRASP
By similarity.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Sequence similarities: Belongs to the G-protein coupled receptor 3 family.
Research Articles on Grm3
Similar Products
Product Notes
The Grm3 grm3 (Catalog #AAA658439) is a Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's mGluR2,3 peptide can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the Grm3 grm3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "mGluR2,3 peptide, Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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