Western Blot (WB)
(SYT2 Antibody (Center) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SYT2 antibody detected the SYT2 protein (arrow).)
Rabbit anti-Human SYT2 Polyclonal Antibody | anti-SYT2 antibody
SYT2, ID (SYT2, Synaptotagmin-2, Synaptotagmin II)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Western Blot (WB)
(SYT2 Antibody (Center) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SYT2 antibody detected the SYT2 protein (arrow).)
Western Blot (WB)
(SYT2 Antibody (Center) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SYT2 antibody detected the SYT2 protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994 [PubMed 8058779]).[supplied by OMIM, Mar 2008]
Uniprot Description
Function: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone
By similarity.
Cofactor: Binds 3 calcium ions per subunit. The ions are bound to the C2 domains
By similarity.
Subunit structure: Homotetramer
Probable. Interacts with stonin 2
By similarity. Interacts with SCAMP5. Ref.3
Subcellular location: Cytoplasmic vesicle › secretory vesicle › synaptic vesicle membrane; Single-pass membrane protein
By similarity. Cytoplasmic vesicle › secretory vesicle › chromaffin granule membrane; Single-pass membrane protein
By similarity. Note: Synaptic vesicles and chromaffin granules
By similarity.
Domain: The first C2 domain mediates Ca2+-dependent phospholipid binding
By similarity.The second C2 domain mediates interaction with Stonin 2
By similarity.
Sequence similarities: Belongs to the synaptotagmin family.Contains 2 C2 domains.
Research Articles on SYT2
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Product Notes
The SYT2 syt2 (Catalog #AAA647833) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SYT2, ID (SYT2, Synaptotagmin-2, Synaptotagmin II) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SYT2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the SYT2 syt2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SYT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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