Western Blot (WB)
(QTRT1 Antibody (C-term) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the QTRT1 antibody detected the QTRT1 protein (arrow).)
Rabbit anti-Human QTRT1 Polyclonal Antibody | anti-QTRT1 antibody
QTRT1, CT (QTRT1, TGT, TGUT, Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Western Blot (WB)
(QTRT1 Antibody (C-term) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the QTRT1 antibody detected the QTRT1 protein (arrow).)
Western Blot (WB)
(QTRT1 Antibody (C-term) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the QTRT1 antibody detected the QTRT1 protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the catalytic subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine and tyrosine. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, Feb 2012]
Uniprot Description
Function: Interacts with QTRTD1 to form an active queuine tRNA-ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GUN anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
By similarity.
Catalytic activity: Guanine34 in tRNA + queuine = queuosine34 in tRNA + guanine.
Cofactor: Binds 1 zinc ion per subunit
By similarity.
Pathway: tRNA modification; tRNA-queuosine biosynthesis.
Subunit structure: Interacts with QTRTD1
By similarity.
Subcellular location: Cytoplasm
By similarity. Mitochondrion
By similarity. Nucleus
By similarity. Note: Weakly associates with mitochondria, possibly via QTRTD1
By similarity.
Sequence similarities: Belongs to the queuine tRNA-ribosyltransferase family.
Sequence caution: The sequence AAH15350.1 differs from that shown. Reason: Erroneous initiation.
Research Articles on QTRT1
Similar Products
Product Notes
The QTRT1 qtrt1 (Catalog #AAA647000) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The QTRT1, CT (QTRT1, TGT, TGUT, Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's QTRT1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the QTRT1 qtrt1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "QTRT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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