Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human kidney tissue slide using MBS7600107 (hIST1 Antibody) at dilution of 1:50)
Rabbit hIST1 Polyclonal Antibody | anti-hIST1 antibody
hIST1 Rabbit Polyclonal
Immunogen Affinity Purified
Immunogen Affinity Purified
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human kidney tissue slide using MBS7600107 (hIST1 Antibody) at dilution of 1:50)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human kidney tissue slide using MBS7600107 (hIST1 Antibody) at dilution of 1:50)
Western Blot (WB)
(mouse liver tissue were subjected to SDS PAGE followed by western blot with MBS7600107 (hIST1 Antibody) at dilution of 1:1000)
Western Blot (WB)
(mouse liver tissue were subjected to SDS PAGE followed by western blot with MBS7600107 (hIST1 Antibody) at dilution of 1:1000)
NCBI and Uniprot Product Information
NCBI Description
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]
Uniprot Description
H1F1: Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation. Belongs to the histone H1/H5 family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 6p21.3
Cellular Component: nuclear chromatin; nucleosome
Molecular Function: chromatin DNA binding; protein binding
Biological Process: nucleosome assembly; spermatogenesis
Research Articles on hIST1
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Product Notes
The hIST1 hist1h1a (Catalog #AAA7600107) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The hIST1 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's hIST1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB), Immunofluorescence (IF). Researchers should empirically determine the suitability of the hIST1 hist1h1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "hIST1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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