Western Blot (WB)
(UROC1 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the UROC1 antibody detected the UROC1 protein (arrow).)
Rabbit anti-Human UROC1 Polyclonal Antibody | anti-UROC1 antibody
UROC1, ID (UROC1, Urocanate hydratase, Imidazolonepropionate hydrolase)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50
Western Blot (WB)
(UROC1 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the UROC1 antibody detected the UROC1 protein (arrow).)
Western Blot (WB)
(UROC1 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the UROC1 antibody detected the UROC1 protein (arrow).)
Immunohistochemistry (IHC)
(UROC1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of UROC1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(UROC1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of UROC1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an enzyme involved in histidine catabolism, metabolizing urocanic acid to formiminoglutamic acid. The gene product is known to protect the skin from ultra violet rays and is contained in human sweat. Deficiency of this gene product in the liver is an apparent cause of mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Uniprot Description
UROC1: Defects in UROC1 are a cause of urocanase deficiency (UROD). An inborn error of histidine metabolism resulting in urocanic aciduria and neurological manifestations including mental retardation, ataxia, episodic aggressive behavior or exaggerated affection-seeking. Belongs to the urocanase family.
Protein type: Amino Acid Metabolism - histidine; Lyase; EC 4.2.1.49
Chromosomal Location of Human Ortholog: 3q21.3
Cellular Component: cytosol
Molecular Function: urocanate hydratase activity
Biological Process: histidine catabolic process to glutamate and formamide; histidine catabolic process; histidine catabolic process to glutamate and formate
Disease: Urocanase Deficiency
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Product Notes
The UROC1 uroc1 (Catalog #AAA642362) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The UROC1, ID (UROC1, Urocanate hydratase, Imidazolonepropionate hydrolase) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's UROC1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Western Blot, Immunohistochemistry, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50. Researchers should empirically determine the suitability of the UROC1 uroc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UROC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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