IL-6:Fc Active Protein | IL4 active protein
IL-6, Recombinant, Mouse:Fc (Interleukin-6, B Cell Hybridoma Growth Factor, Interleukin HP-1)
Gene Names
IL4; IL2; BSF-1
Purity
Highly Purified>95% (SDS-PAGE)
Synonyms
IL-6:Fc; IL-6; Recombinant; Mouse:Fc (Interleukin-6; B Cell Hybridoma Growth Factor; Interleukin HP-1); IL4 active protein
Host
Human, Mouse, HEK 293 cells
Purity/Purification
Highly Purified
>95% (SDS-PAGE)
>95% (SDS-PAGE)
Form/Format
Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.
Sequence
The extracellular domain of mouse IL-6 (aa 25-211) is fused at the C-terminus to the Fc portion of human IgG2.
Biological Activity
Promotes growth of hybridoma/plasma cells at concentration <0.1ng /ml.
Preparation and Storage
Short-term Storage: +4 degree C
Long-term Storage: -20 degree C
Stable for at least 1 year after receipt when stored at -20 degree C. Working aliquots are stable for up to 3 months when stored at -20 degree C.
Long-term Storage: -20 degree C
Stable for at least 1 year after receipt when stored at -20 degree C. Working aliquots are stable for up to 3 months when stored at -20 degree C.
Related Product Information for IL4 active protein
Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kD-28kD phosphorylated and variably glycosylated molecule. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130). IL-6 is a key factor for the growth of plasma cells.
Product Categories/Family for IL4 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
16,562 Da
NCBI Official Full Name
Interleukin-4
NCBI Official Symbol
IL4
NCBI Official Synonym Symbols
IL2; BSF-1
NCBI Protein Information
interleukin-4; B-cell stimulatory factor 1; lymphocyte stimulatory factor 1
UniProt Protein Name
Interleukin-4
Protein Family
UniProt Gene Name
IL4
UniProt Synonym Gene Names
IL-4; BSF-1
UniProt Entry Name
IL4_RABIT
Uniprot Description
Function: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes
By similarity.
Subcellular location: Secreted.
Sequence similarities: Belongs to the IL-4/IL-13 family.
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Product Notes
The IL4 il4 (Catalog #AAA636196) is an Active Protein produced from Human, Mouse, HEK 293 cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: The extracellu lar domain of mouse IL-6 (aa 25-211) is fused at the C-terminus to the Fc portion of human IgG2. It is sometimes possible for the material contained within the vial of "IL-6:Fc, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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