Western Blot (WB)
(SOCS7 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SOCS7 antibody detected the SOCS7 protein (arrow).)
Rabbit anti-Human SOCS7 Polyclonal Antibody | anti-SOCS7 antibody
SOCS7, CT (SOCS7, NAP4, SOCS6, Suppressor of cytokine signaling 7, Nck, Ash and phospholipase C gamma-binding protein, Nck-associated protein 4) (AP)
Gene Names
SOCS7; NAP4; NCKAP4
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
SOCS7; Polyclonal Antibody; CT (SOCS7; NAP4; SOCS6; Suppressor of cytokine signaling 7; Nck; Ash and phospholipase C gamma-binding protein; Nck-associated protein 4) (AP); Nck-associated protein 4; anti-SOCS7 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Applicable Applications for anti-SOCS7 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
SOCS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 457-486 amino acids from the C-terminal region of human SOCS7.
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(SOCS7 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SOCS7 antibody detected the SOCS7 protein (arrow).)
Western Blot (WB)
(SOCS7 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SOCS7 antibody detected the SOCS7 protein (arrow).)
Related Product Information for anti-SOCS7 antibody
Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
Product Categories/Family for anti-SOCS7 antibody
References
Pazienza, V., et al. J. Gen. Virol. 91 (PT 7), 1678-1686 (2010): Sasi, W., et al. BMC Cancer 10, 178 (2010): Kremer, B.E., et al. Cell 130(5):837-850(2007). Zody, M.C., et al. Nature 440(7087):1045-1049(2006). Banks, A.S., et al. J. Clin. Invest. 115(9):2462-2471(2005).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
37,461 Da
NCBI Official Full Name
suppressor of cytokine signaling 7
NCBI Official Synonym Full Names
suppressor of cytokine signaling 7
NCBI Official Symbol
SOCS7
NCBI Official Synonym Symbols
NAP4; NCKAP4
NCBI Protein Information
suppressor of cytokine signaling 7
UniProt Protein Name
Suppressor of cytokine signaling 7
Protein Family
UniProt Gene Name
SOCS7
UniProt Synonym Gene Names
NAP4; SOCS6
UniProt Entry Name
SOCS7_HUMAN
Research Articles on SOCS7
1. This study showed that increased protein levels of SOCS-4 and SOCS-7 in Alzheimer's disease brains.
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Product Notes
The SOCS7 socs7 (Catalog #AAA6349771) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SOCS7, CT (SOCS7, NAP4, SOCS6, Suppressor of cytokine signaling 7, Nck, Ash and phospholipase C gamma-binding protein, Nck-associated protein 4) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SOCS7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the SOCS7 socs7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SOCS7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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