Vasopressin [Arg8] Peptide | AVPR1A peptide

Vasopressin [Arg8] (free acid)

Cat. Num. AAA633832

• Gene Names: AVPR1A; V1aR; AVPR1; AVPR V1a
• Purity: Highly Purified; ~95%. Purified by HPLC.
• Synonyms: Vasopressin [Arg8]; Vasopressin [Arg8] (free acid); AVPR1A peptide

• Host: Synthetic peptide
• Purity/Purification: Highly Purified; ~95%. Purified by HPLC.
• Form/Format: Supplied as a lyophilized powder.

• Sequence (linear): Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly
• Preparation and Storage: Lyophilized powder may be stored at 4 degree C for short-term only. Stable for 12 months at -20 degree C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Product Categories/Family for AVPR1A peptide

Molecular Biology; MB-Peptides

NCBI and Uniprot Product Information

• NCBI GI #: 4502331
• NCBI GeneID: 552
• NCBI Accession #: NP_000697.1
• NCBI GenBank Nucleotide #: NM_000706.4
• UniProt Accession #: P37288
• Molecular Weight: 46,800 Da
• NCBI Official Full Name: vasopressin V1a receptor
• NCBI Official Synonym Full Names: arginine vasopressin receptor 1A
• NCBI Official Symbol: AVPR1A
• NCBI Official Synonym Symbols: V1aR; AVPR1; AVPR V1a
• NCBI Protein Information: vasopressin V1a receptor; V1a vasopressin receptor; antidiuretic hormone receptor 1A; SCCL vasopressin subtype 1a receptor; V1-vascular vasopressin receptor AVPR1A; vascular/hepatic-type arginine vasopressin receptor
• UniProt Protein Name: Vasopressin V1a receptor
• Protein Family: Vasopressin V1a receptor
• UniProt Gene Name: AVPR1A
• UniProt Synonym Gene Names: AVPR1; V1aR
• UniProt Entry Name: V1AR_HUMAN

NCBI Description

The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq, Jul 2008]

Uniprot Description

AVPR1A: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1

Chromosomal Location of Human Ortholog: 12q14-q15

Cellular Component: integral to plasma membrane; plasma membrane; cytoplasmic vesicle; endosome

Molecular Function: protein binding; protein kinase C binding; V1A vasopressin receptor binding; peptide hormone binding; peptide binding; vasopressin receptor activity

Biological Process: blood circulation; positive regulation of glutamate secretion; positive regulation of cellular pH reduction; cellular response to water deprivation; positive regulation of systemic arterial blood pressure; elevation of cytosolic calcium ion concentration; positive regulation of cell proliferation; response to corticosterone stimulus; positive regulation of prostaglandin biosynthetic process; penile erection; grooming behavior; generation of precursor metabolites and energy; maternal behavior; myotube differentiation; calcium-mediated signaling; positive regulation of heart rate; social behavior; positive regulation of cell growth; cellular response to hormone stimulus; negative regulation of female receptivity; G-protein coupled receptor protein signaling pathway; telencephalon development; negative regulation of transmission of nerve impulse; regulation of systemic arterial blood pressure by vasopressin; phospholipase C activation; positive regulation of vasoconstriction; sperm ejaculation