Rabbit anti-Human, Mouse OSGIN1 Polyclonal Antibody | anti-OSGIN1 antibody

OSGIN1, CT (OSGIN1, OKL38, Oxidative stress-induced growth inhibitor 1, Ovary, kidney and liver protein 38, Pregnancy-induced growth inhibitor OKL38) (AP)

Cat. Num. AAA6329735

• Gene Names: OSGIN1; BDGI; OKL38
• Reactivity: Human, Mouse
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: OSGIN1; Polyclonal Antibody; CT (OSGIN1; OKL38; Oxidative stress-induced growth inhibitor 1; Ovary; kidney and liver protein 38; Pregnancy-induced growth inhibitor OKL38) (AP); Pregnancy-induced growth inhibitor OKL38; anti-OSGIN1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

• Applicable Applications for anti-OSGIN1 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: OSGIN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 482-510 amino acids from the C-terminal region of human OSGIN1.
• Conjugate: AP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(OSGIN1 Antibody (C-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the OSGIN1 antibody detected the OSGIN1 protein (arrow).)

Related Product Information for anti-OSGIN1 antibody

OSGIN1 regulates the differentiation and proliferation of normal cells through the regulation of cell death.

Product Categories/Family for anti-OSGIN1 antibody

Antibodies; Proteins

References

Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010). Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010). Yao, H., et al. J. Biol. Chem. 283(29):20060-20068(2008). Ong, C.K., et al. Oncogene 26(8):1155-1165(2007). Wang, T., et al. J. Biol. Chem. 280(6):4374-4382(2005).

NCBI and Uniprot Product Information

• NCBI GI #: 118572590
• NCBI GeneID: 29948
• UniProt Accession #: Q9UJX0
• NCBI Official Synonym Full Names: oxidative stress induced growth inhibitor 1
• NCBI Official Symbol: OSGIN1
• NCBI Official Synonym Symbols: BDGI; OKL38
• NCBI Protein Information: oxidative stress-induced growth inhibitor 1
• UniProt Protein Name: Oxidative stress-induced growth inhibitor 1
• Protein Family: Oxidative stress-induced growth inhibitor
• UniProt Gene Name: OSGIN1
• UniProt Synonym Gene Names: OKL38; huOKL38

NCBI Description

This gene encodes an oxidative stress response protein that regulates cell death. Expression of the gene is regulated by p53 and is induced by DNA damage. The protein regulates apoptosis by inducing cytochrome c release from mitochondria. It also appears to be a key regulator of both inflammatory and anti-inflammatory molecules. The loss of this protein correlates with uncontrolled cell growth and tumor formation. Naturally occurring read-through transcription exists between this gene and the neighboring upstream malonyl-CoA decarboxylase (MLYCD) gene, but the read-through transcripts are unlikely to produce a protein product. [provided by RefSeq, Aug 2011]

Uniprot Description

Regulates the differentiation and proliferation of normal cells through the regulation of cell death.