Western Blot (WB)
(Western Blot analysis of OSGIN1 expression in transfected 293T cell line by OSGIN1 polyclonal antibody. Lane 1: OKL38 transfected lysate (52.47kD). Lane 2: Non-transfected lysate.)
Mouse anti-Human OKL38 Polyclonal Antibody | anti-OSGIN1 antibody
OKL38 (OSGIN1, Oxidative Stress-induced Growth Inhibitor 1, Ovary, Kidney and Liver Protein 38, huOKL38, Pregnancy-induced Growth Inhibitor OKL38, BDGI, huOKL38)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Western Blot (WB)
(Western Blot analysis of OSGIN1 expression in transfected 293T cell line by OSGIN1 polyclonal antibody. Lane 1: OKL38 transfected lysate (52.47kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of OSGIN1 expression in transfected 293T cell line by OSGIN1 polyclonal antibody. Lane 1: OKL38 transfected lysate (52.47kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an oxidative stress response protein that regulates cell death. Expression of the gene is regulated by p53 and is induced by DNA damage. The protein regulates apoptosis by inducing cytochrome c release from mitochondria. It also appears to be a key regulator of both inflammatory and anti-inflammatory molecules. The loss of this protein correlates with uncontrolled cell growth and tumor formation. Naturally occurring read-through transcription exists between this gene and the neighboring upstream malonyl-CoA decarboxylase (MLYCD) gene, but the read-through transcripts are unlikely to produce a protein product. [provided by RefSeq, Aug 2011]
Uniprot Description
OSGIN1: Regulates the differentiation and proliferation of normal cells through the regulation of cell death. Belongs to the OKL38 family. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 16q23.3
Molecular Function: growth factor activity
Biological Process: positive regulation of apoptosis; multicellular organismal development; negative regulation of cell growth; cell differentiation
Research Articles on OSGIN1
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Product Notes
The OSGIN1 osgin1 (Catalog #AAA6006871) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The OKL38 (OSGIN1, Oxidative Stress-induced Growth Inhibitor 1, Ovary, Kidney and Liver Protein 38, huOKL38, Pregnancy-induced Growth Inhibitor OKL38, BDGI, huOKL38) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's OKL38 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the OSGIN1 osgin1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MSSSRKDHLG ASSSEPLPVI IVGNGPSGIC LSYLLSGYTP YTKPDAIHPH PLLQRKLTEA PGVSILDQDL DYLSEGLEGR SQSPVALLFD ALLRPDTDFG GNMKSVLTWK HRKEHAIPHV VLGRNLPGGA WHSIEGSMVI LSQGQWMGLP DLEVKDWMQK KRRGLRNSRA TAGDIAHYYR DYVVKKGLGH NFVSGAVVTA VEWGTPDPSS CGAQDSSPLF QVSGFLTRNQ AQQPFSLWAR NVVLATGTFD SPARLGIPGE ALPFIHHELS ALEAATRVGA VTPASDPVLI IGAGLSAADA VLYARHYNIP VIHAFRRAVD DPGLVFNQLP KMLYPEYHKV HQMMREQSIL SPSPYEGYRS LPRHQLLCFK EDCQAVFQDL EGVEKVFGVS LVLVLIGSHP DLSFLPGAGA DFAVDPDQPL SAKRNPIDVD PFTYQSTRQE GLYAMGPLAG DNFVRFVQGG ALAVASSLLR KETRKPP. It is sometimes possible for the material contained within the vial of "OKL38, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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