Western Blot (WB)
(MOUSE Mavs Antibody (N-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the MOUSE Mavs antibody detected the MOUSE Mavs protein (arrow).)
Rabbit anti-Mouse Mavs Polyclonal Antibody | anti-Mavs antibody
Mavs, NT (Mavs, Ips1, Visa, Mitochondrial antiviral-signaling protein, CARD adapter inducing interferon beta, Interferon beta promoter stimulator protein 1, Virus-induced-signaling adapter) (PE)
Gene Names
Mavs; Visa; IPS-1; cardif; D430028G21Rik
Reactivity
Mouse
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
Mavs; Polyclonal Antibody; NT (Mavs; Ips1; Visa; Mitochondrial antiviral-signaling protein; CARD adapter inducing interferon beta; Interferon beta promoter stimulator protein 1; Virus-induced-signaling adapter) (PE); mitochondrial antiviral-signaling protein; Virus-induced-signaling adapter; anti-Mavs antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Applicable Applications for anti-Mavs antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
MOUSE Mavs antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse Mavs.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(MOUSE Mavs Antibody (N-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the MOUSE Mavs antibody detected the MOUSE Mavs protein (arrow).)
Western Blot (WB)
(MOUSE Mavs Antibody (N-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the MOUSE Mavs antibody detected the MOUSE Mavs protein (arrow).)
Related Product Information for anti-Mavs antibody
Required for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis (By similarity).
Product Categories/Family for anti-Mavs antibody
References
Ichinohe, T., et al. Nat. Immunol. 11(5):404-410(2010). DeWitte-Orr, S.J., et al. PLoS Pathog. 6 (3), E1000829 (2010): Suthar, M.S., et al. PLoS Pathog. 6 (2), E1000757 (2010): Dong, X., et al. PLoS Pathog. 6 (7), E1001001 (2010): Faul, E.J., et al. PLoS Pathog. 6 (7), E1001016 (2010).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53,399 Da
NCBI Official Full Name
mitochondrial antiviral-signaling protein isoform 1
NCBI Official Synonym Full Names
mitochondrial antiviral signaling protein
NCBI Official Symbol
Mavs
NCBI Official Synonym Symbols
Visa; IPS-1; cardif; D430028G21Rik
NCBI Protein Information
mitochondrial antiviral-signaling protein
UniProt Protein Name
Mitochondrial antiviral-signaling protein
Protein Family
UniProt Gene Name
Mavs
UniProt Synonym Gene Names
Ips1; Visa; MAVS; Cardif; IPS-1; VISA
UniProt Entry Name
MAVS_MOUSE
Research Articles on Mavs
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Product Notes
The Mavs mavs (Catalog #AAA6319242) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Mavs, NT (Mavs, Ips1, Visa, Mitochondrial antiviral-signaling protein, CARD adapter inducing interferon beta, Interferon beta promoter stimulator protein 1, Virus-induced-signaling adapter) (PE) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Mavs can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the Mavs mavs for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Mavs, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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