Rabbit anti-Human, Mouse LRRC4C Polyclonal Antibody | anti-LRRC4C antibody

LRRC4C, ID (LRRC4C, KIAA1580, NGL1, Leucine-rich repeat-containing protein 4C, Netrin-G1 ligand) (APC)

Cat. Num. AAA6317187

• Gene Names: LRRC4C; NGL1; NGL-1
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: LRRC4C; Polyclonal Antibody; ID (LRRC4C; KIAA1580; NGL1; Leucine-rich repeat-containing protein 4C; Netrin-G1 ligand) (APC); Netrin-G1 ligand; anti-LRRC4C antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
• Sequence Length: 640

• Applicable Applications for anti-LRRC4C antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: LRRC4C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-343 amino acids from the Central region of human LRRC4C.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(LRRC4C Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the LRRC4C antibody detected the LRRC4C protein (arrow).)

Related Product Information for anti-LRRC4C antibody

NGL1 is a specific binding partner for netrin G1 (NTNG1; MIM 608818), which is a member of the netrin family of axon guidance molecules (Lin et al., 2003 [PubMed 14595443]).[supplied by OMIM].

Product Categories/Family for anti-LRRC4C antibody

Antibodies; Netrin

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Sokolowski, M., et al. Mol. Psychiatry 15(1):10-11(2010). Hsu, Y.H., et al. PLoS Genet. 6 (6), E1000977 (2010): Lin, J.C., et al. Nat. Neurosci. 6(12):1270-1276(2003). Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003).

NCBI and Uniprot Product Information

• NCBI GI #: 51317373
• NCBI GeneID: 57689
• NCBI Accession #: NP_065980.1
• NCBI GenBank Nucleotide #: NP_065980.1
• UniProt Accession #: Q9HCJ2
• NCBI Official Full Name: leucine-rich repeat-containing protein 4C
• NCBI Official Synonym Full Names: leucine rich repeat containing 4C
• NCBI Official Symbol: LRRC4C
• NCBI Official Synonym Symbols: NGL1; NGL-1
• NCBI Protein Information: leucine-rich repeat-containing protein 4C
• UniProt Protein Name: Leucine-rich repeat-containing protein 4C
• Protein Family: Leucine-rich repeat-containing protein
• UniProt Gene Name: LRRC4C
• UniProt Synonym Gene Names: KIAA1580; NGL1; NGL-1
• UniProt Entry Name: LRC4C_HUMAN

NCBI Description

NGL1 is a specific binding partner for netrin G1 (NTNG1; MIM 608818), which is a member of the netrin family of axon guidance molecules (Lin et al., 2003 [PubMed 14595443]).[supplied by OMIM, Mar 2008]

Uniprot Description

LRRC4C: May promote neurite outgrowth of developing thalamic neurons.

Protein type: Membrane protein, integral; Cell development/differentiation

Chromosomal Location of Human Ortholog: 11p12

Cellular Component: postsynaptic membrane; extracellular space; membrane; integral to membrane; cell junction

Molecular Function: protein binding

Biological Process: regulation of axonogenesis