Rabbit anti-Human, Mouse PPP1R3C Polyclonal Antibody | anti-PPP1R3C antibody

PPP1R3C (Protein Phosphatase 1 Regulatory Subunit 3C, Protein Phosphatase 1 Regulatory Subunit 5, PP1 Subunit R5, Protein Targeting to Glycogen, PTG, PPP1R5)

Cat. Num. AAA631257

• Gene Names: PPP1R3C; PPP1R5
• Reactivity: Human, Mouse
• Applications: Western Blot, Immunoprecipitation
• Purity: Serum; Serum
• Synonyms: PPP1R3C; Polyclonal Antibody; PPP1R3C (Protein Phosphatase 1 Regulatory Subunit 3C; Protein Phosphatase 1 Regulatory Subunit 5; PP1 Subunit R5; Protein Targeting to Glycogen; PTG; PPP1R5); Anti -PPP1R3C (Protein Phosphatase 1 Regulatory Subunit 3C; anti-PPP1R3C antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Specificity: Recognizes human PPP1R3C. Species Crossreactivity: mouse.
• Purity/Purification: Serum; Serum
• Form/Format: Supplied as a liquid.

• Applicable Applications for anti-PPP1R3C antibody: Western Blot (WB), Immunoprecipitation (IP)
• Application Notes: Suitable for use in Western Blot and Immunoprecipitation.
• Immunogen: PPP1R3C (AAH12625.1, 1-317aa) full-length human protein.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, 11c7entrifuge the original vial after thawing and prior to removing the cap.

Related Product Information for anti-PPP1R3C antibody

Protein phosphatase-1 (PP1; see MIM 176875) participates in the regulation of a wide variety of cellular functions by reversible protein phosphorylation. The ability of PP1 to regulate diverse functions resides in its capacity to interact with a variety of regulatory subunits that may target PP1 to specific subcellular locations, modulate its substrate specificity, and allow its activity to be responsive to extracellular signals. Several targeting subunits of PP1 have been identified, including PPP1R5, the glycogen-binding subunits PPP1R3 (MIM 600917) and PPP1R4, and the nuclear inhibitor of PP1 (PPP1R8; MIM 602636).

Product Categories/Family for anti-PPP1R3C antibody

Antibodies; Abs to Enzymes; Phosphatase

NCBI and Uniprot Product Information

• NCBI GI #: 4885559
• NCBI GeneID: 5507
• NCBI Accession #: NP_005389.1
• NCBI GenBank Nucleotide #: NM_005398.4
• UniProt Accession #: Q9UQK1; O95686; B2R7X0; Q8TDR5
• Molecular Weight: 36,445 Da
• NCBI Official Full Name: protein phosphatase 1 regulatory subunit 3C
• NCBI Official Synonym Full Names: protein phosphatase 1, regulatory (inhibitor) subunit 3C
• NCBI Official Symbol: PPP1R3C
• NCBI Official Synonym Symbols: PPP1R5
• NCBI Protein Information: protein phosphatase 1 regulatory subunit 3C; PTG; PP1 subunit R5; OTTHUMP00000020089; protein targeting to glycogen; protein phosphatase 1 regulatory subunit 5; Phosphatase 1, regulatory inhibitor subunit 5
• UniProt Protein Name: Protein phosphatase 1 regulatory subunit 3C
• Protein Family: Protein phosphatase 1 regulatory
• UniProt Gene Name: PPP1R3C
• UniProt Synonym Gene Names: PPP1R5
• UniProt Entry Name: PPR3C_HUMAN

NCBI Description

Protein phosphatase-1 (PP1; see MIM 176875) participates in the regulation of a wide variety of cellular functions by reversible protein phosphorylation. The ability of PP1 to regulate diverse functions resides in its capacity to interact with a variety of regulatory subunits that may target PP1 to specific subcellular locations, modulate its substrate specificity, and allow its activity to be responsive to extracellular signals. Several targeting subunits of PP1 have been identified, including PPP1R5, the glycogen-binding subunits PPP1R3 (MIM 600917) and PPP1R4, and the nuclear inhibitor of PP1 (PPP1R8; MIM 602636).[supplied by OMIM]

Uniprot Description

PPP1R3C: Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types.

Protein type: Motility/polarity/chemotaxis; Protein phosphatase, regulatory subunit

Chromosomal Location of Human Ortholog: 10q23-q24

Cellular Component: cytosol

Molecular Function: protein binding; protein serine/threonine phosphatase activity; protein phosphatase binding

Biological Process: glycogen biosynthetic process; dephosphorylation; carbohydrate metabolic process; glucose metabolic process; pathogenesis