Rabbit STAT 5 Polyclonal Antibody | anti-Stat92E antibody

STAT 5, phosphorylated (Tyr694) (BSA Glycerol & Azide Free) (Signal Transducer and Activator of Transcription 5)

Cat. Num. AAA631185

• Gene Names: Stat92E; CG4257; d-STAT; D-stat; D-Stat; D-STAT; D-stat/stat92E; DmelCG4257; DmSTAT; DRODSRC; DSRC; dstat; dSTAT; Dstat; DSTAT; Dstat 92E; dSTAT92E; Dstat92E; dSTAT92E/marelle; l(3)06346; l(3)j6C8; mrl; mrL; mrl stat92E; pSTAT; SD-stat; stat; Stat; STAT; STAT 92E
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by sequential epitope-specific chromatography.
• Synonyms: STAT 5; Polyclonal Antibody; phosphorylated (Tyr694) (BSA Glycerol & Azide Free) (Signal Transducer and Activator of Transcription 5); Anti -STAT 5; anti-Stat92E antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes mouse STAT5 phosphorylated at Tyr694. Species Sequence Homology
• Purity/Purification: Affinity Purified; Purified by sequential epitope-specific chromatography.
• Form/Format: Supplied as a liquid in PBS. No stabilizing proteins added. No preservative added. Also available with BSA & Azide. See S7972-07.

• Applicable Applications for anti-Stat92E antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.; Dilution: Western Blot: 1:1000.
• Immunogen: Synthetic phosphopeptide derived from the region of human STAT5a that contains tyrosine 694.
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Related Product Information for anti-Stat92E antibody

Signal Transducer and Activator of Transcription 5 (STAT5, consists of isoforms a and b) is a ~95kD member of a family of transcription factors that are activated to regulate gene transcription in response to multiple hematopoietic cytokines and growth factors. STAT5 is involved in normal cSignal Transducer and Activator of Transcription 5 (STAT5, consists of isoforms a and b) is a ~95kD member of a family of transcription factors that are activated to regulate gene transcription in response to multiple hematopoietic cytokines and growth factors. STAT5 is involved in normal cell cycle, survival and apoptosis and is implicated in leukaemogenesis and angiogenesis, as it has been found to be constitutively active in many leukemic cell lines. STAT5 activated by phosphorylation of tyrosine 694 in STAT5a (tyrosine 699 in STAT5b), a major Src phosphorylation site that is critical for STAT5 dimerization, translocation and binding to DNA. Phosphorylation of tyrosine 694 is also important in mediating erythropoietin-induced signaling and prolactin-induced development and differentiation of mammary epithelial cells.

Product Categories/Family for anti-Stat92E antibody

Antibodies; Abs to Transcription Factors; STAT

NCBI and Uniprot Product Information

• NCBI GI #: 442620068
• NCBI GeneID: 42428
• NCBI Accession #: NP_001262762.1
• NCBI GenBank Nucleotide #: NM_001275833.1
• UniProt Accession #: Q24151; Q0KI43; Q24181; Q59DV7; Q5BIB0; Q8IN54; Q8SX55; Q9VDL8
• Molecular Weight: 86,415 Da
• NCBI Official Full Name: Signal-transducer and activator of transcription protein at 92E, isoform M
• NCBI Official Synonym Full Names: Signal-transducer and activator of transcription protein at 92E
• NCBI Official Symbol: Stat92E
• NCBI Official Synonym Symbols: CG4257; d-STAT; D-stat; D-Stat; D-STAT; D-stat/stat92E; DmelCG4257; DmSTAT; DRODSRC; DSRC; dstat; dSTAT; Dstat; DSTAT; Dstat 92E; dSTAT92E; Dstat92E; dSTAT92E/marelle; l(3)06346; l(3)j6C8; mrl; mrL; mrl stat92E; pSTAT; SD-stat; stat; Stat; STAT; STAT 92E;
• NCBI Protein Information: CG4257 gene product from transcript CG4257-RH; CG4257-PB; CG4257-PC; CG4257-PE; CG4257-PF; CG4257-PG; CG4257-PH; CG4257-PI; CG4257-PJ; CG4257-PK; CG4257-PL; CG4257-PM; Signal-transducer and activator of transcription protein; Signal-transducer and activator of transcription protein at 92E; Stat92E-PB; Stat92E-PC; Stat92E-PE; Stat92E-PF; Stat92E-PG; Stat92E-PH; Stat92E-PI; Stat92E-PJ; Stat92E-PK; Stat92E-PL; Stat92E-PM; marelle; signal transducer and activator of transcription; signal transducers and activator of transcription
• UniProt Protein Name: Signal transducer and transcription activator
• UniProt Gene Name: Stat92E
• UniProt Synonym Gene Names: MARE; mrL; Stat; d-STAT
• UniProt Entry Name: STAT_DROME

Uniprot Description

STAT5A: Signal transduction and activation of transcription. Plays an important role in the segmental pattern formation in the early embryo by activating specific stripes of pair rule gene expression. The Janus kinase-STAT pathway is connected to drosophila early development

Protein type: Oncoprotein; DNA-binding; Transcription factor; Motility/polarity/chemotaxis

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; signal transducer activity; DNA binding; transcription factor activity

Biological Process: oogenesis; negative regulation of Wnt receptor signaling pathway; somatic stem cell maintenance; lymph gland hemopoiesis; primary sex determination; stem cell division; compound eye development; defense response; signal transduction; negative regulation of antimicrobial humoral response; segment specification; regulation of JAK-STAT cascade; regulation of transcription, DNA-dependent; hemocyte proliferation; positive regulation of cell proliferation; somatic stem cell division; hemopoiesis; epithelial cell fate determination, open tracheal system; nervous system development; germ-line stem cell division; imaginal disc-derived wing morphogenesis; larval somatic muscle development; stem cell maintenance; oocyte localization during germarium-derived egg chamber formation; germ-line stem cell maintenance; ovarian follicle cell stalk formation; JAK-STAT cascade; humoral immune response; border follicle cell migration; sex determination; long-term memory; open tracheal system development; cell dedifferentiation; lamellocyte differentiation; hindgut morphogenesis; positive regulation of defense response to virus by host; eye-antennal disc morphogenesis; blastoderm segmentation