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Mouse anti-Human CD240DCE Monoclonal Antibody | anti-CD240DCE antibody

CD240DCE (APC)

Gene Names
RHCE; RH; RHC; RHE; Rh4; RHPI; RhVI; RH30A; RHIXB; RhVIII; CD240CE; RhIVb(J)
Reactivity
Human
Applications
Immunoprecipitation
Purity
Purified
Synonyms
CD240DCE; Monoclonal Antibody; CD240DCE (APC); anti-CD240DCE antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3H2011
Specificity
Recognizes human CD240DCE and erythrocytes of normal Rh types but does not recognize Rhnull erythrocytes. Reacts with 31kD and 35-52kD proteins which were designated CD240DCE at the 7th leukocyte typing workshop.
Purity/Purification
Purified
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-CD240DCE antibody
Immunoprecipitation (IP)
Immunogen
Human erythrocytes
Conjugate
APC
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Product Categories/Family for anti-CD240DCE antibody
References
1. Mouro-Chanteloup, I. et al. (2002) Cell-surface expression of RhD blood group polypeptide is posttranscriptionally regulated by the RhAG glycoprotein. Blood. 100 (3): 1038-47. 2. Mouro-Chanteloup, I. et al. (2003) Evidence that the red cell skeleton protein 4.2 interacts with the Rh membrane complex member CD47. Blood. 101 (1): 338-44.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
26,852 Da
NCBI Official Full Name
blood group Rh(CE) polypeptide isoform 1
NCBI Official Synonym Full Names
Rh blood group, CcEe antigens
NCBI Official Symbol
RHCE
NCBI Official Synonym Symbols
RH; RHC; RHE; Rh4; RHPI; RhVI; RH30A; RHIXB; RhVIII; CD240CE; RhIVb(J)
NCBI Protein Information
blood group Rh(CE) polypeptide; blood group Rh(CE) polypeptide; RHCE blood group variant Crawford antigen Rh43; Rh blood group C antigen; Rh blood group antigen Evans; Rh polypeptide I; Rhesus blood group CE protein; Rhesus blood group E antigen; Rhesus b
UniProt Protein Name
Blood group Rh(CE) polypeptide
UniProt Gene Name
RHCE
UniProt Synonym Gene Names
RHC; RHE; RhPI
UniProt Entry Name
RHCE_HUMAN

NCBI Description

The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease. Alternative splicing of this gene results in four transcript variants encoding four different isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

RHCE: May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. 14 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p36.11

Cellular Component: integral to plasma membrane

Molecular Function: ammonium transmembrane transporter activity

Disease: Blood Group--rhesus System E Polypeptide

Research Articles on CD240DCE

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Product Notes

The CD240DCE rhce (Catalog #AAA6268414) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD240DCE (APC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD240DCE can be used in a range of immunoassay formats including, but not limited to, Immunoprecipitation (IP). Researchers should empirically determine the suitability of the CD240DCE rhce for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD240DCE, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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