Western Blot (WB)
(Western blot analysis of NAT2 Antibody (C-term) in mouse kidney tissue lysates (35ug/lane).NAT2 (arrow) was detected using the purified Pab.)
Rabbit anti-Human, Mouse NAT2 Polyclonal Antibody | anti-NAT2 antibody
NAT2, CT (N-acetyltransferase Type 2, NAT-2, Arylamine N-acetyltransferase 2, Arylamide Acetylase 2, AAC2, Polymorphic Arylamine N-acetyltransferase, PNAT)
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100
Western Blot (WB)
(Western blot analysis of NAT2 Antibody (C-term) in mouse kidney tissue lysates (35ug/lane).NAT2 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of NAT2 Antibody (C-term) in mouse kidney tissue lysates (35ug/lane).NAT2 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of NAT2 (arrow) using rabbit polyclonal NAT2 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the NAT2 gene.)
Western Blot (WB)
(Western blot analysis of NAT2 (arrow) using rabbit polyclonal NAT2 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the NAT2 gene.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human hepatocarcinoma with NAT2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human hepatocarcinoma with NAT2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of HepG2 cells using NAT2 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of HepG2 cells using NAT2 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq]
Uniprot Description
NAT2: Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens. Belongs to the arylamine N-acetyltransferase family.
Protein type: EC 2.3.1.5; Acetyltransferase; Translation; Xenobiotic Metabolism - drug metabolism - other enzymes; Secondary Metabolites Metabolism - caffeine
Chromosomal Location of Human Ortholog: 8p22
Cellular Component: cytosol
Molecular Function: arylamine N-acetyltransferase activity
Biological Process: xenobiotic metabolic process
Disease: Acetylation, Slow
Research Articles on NAT2
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Product Notes
The NAT2 nat2 (Catalog #AAA626733) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NAT2, CT (N-acetyltransferase Type 2, NAT-2, Arylamine N-acetyltransferase 2, Arylamide Acetylase 2, AAC2, Polymorphic Arylamine N-acetyltransferase, PNAT) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NAT2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Dilution: ELISA: 1:1,000 Western Blot: 1:100-1:500 Immunohistochemistry: 1:50-1:100. Researchers should empirically determine the suitability of the NAT2 nat2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NAT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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