Rabbit anti-Human ELAVL1 Polyclonal Antibody | anti-ELAVL1 antibody

ELAVL1 (Hu-antigen R, HuR, ELAV-like Protein 1, HUR) (PE)

Cat. Num. AAA6377216

• Gene Names: ELAVL1; HUR; Hua; MelG; ELAV1
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ELAVL1; Polyclonal Antibody; ELAVL1 (Hu-antigen R; HuR; ELAV-like Protein 1; HUR) (PE); anti-ELAVL1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human ELAVL1.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-ELAVL1 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human ELAVL1, aa1-326 (NP_001410.2).
• Immunogen Sequence: MSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNKSHK
• Conjugate: PE
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(ELAVL1 rabbit polyclonal antibody. Western Blot analysis of ELAVL1 expression in A-431.)

Western Blot (WB)

(Western Blot analysis of ELAVL1 expression in transfected 293T cell line by ELAVL1 polyclonal antibody. Lane 1: ELAVL1 transfected lysate (36.1kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-ELAVL1 antibody

A member of the ELAVL protein family, ELAVL1 contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It destabilizes mRNAs and thereby regulates gene expression.

Product Categories/Family for anti-ELAVL1 antibody

Antibodies; Transcription Factors

NCBI and Uniprot Product Information

• NCBI GI #: 34189624
• NCBI GeneID: 1994
• Molecular Weight: 38,996 Da
• NCBI Official Full Name: Homo sapiens ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R), mRNA
• NCBI Official Synonym Full Names: ELAV like RNA binding protein 1
• NCBI Official Symbol: ELAVL1
• NCBI Official Synonym Symbols: HUR; Hua; MelG; ELAV1
• NCBI Protein Information: ELAV-like protein 1
• Protein Family: ELAV-like protein

NCBI Description

The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012]