Rabbit Synaptotagmin I/II Polyclonal Antibody | anti-SYT2 antibody
Synaptotagmin I/II (Synaptotagmin-1, SytI, p65, SYT1, SVP65, SYT, Synaptotagmin-2, SytII, SYT2)
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Dilution: Western Blot:1:500-1:1,000
NCBI and Uniprot Product Information
NCBI Description
Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994 [PubMed 8058779]).[supplied by OMIM, Mar 2008]
Uniprot Description
SYT2: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. Belongs to the synaptotagmin family.
Protein type: Calcium-binding; Lipid-binding; Membrane protein, integral; Vesicle
Chromosomal Location of Human Ortholog: 1q32.1
Cellular Component: synaptic vesicle membrane; intracellular membrane-bound organelle; integral to membrane; plasma membrane; cell junction
Molecular Function: protein binding; calcium-dependent phospholipid binding; transporter activity; calcium ion binding
Biological Process: transport; pathogenesis
Disease: Myasthenic Syndrome, Presynaptic, Congenital, With Or Without Motor Neuropathy
Research Articles on SYT2
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Product Notes
The SYT2 syt2 (Catalog #AAA624253) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Synaptotagmin I/II (Synaptotagmin-1, SytI, p65, SYT1, SVP65, SYT, Synaptotagmin-2, SytII, SYT2) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Synaptotagmin I/II can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Dilution: Western Blot:1:500-1:1,000. Researchers should empirically determine the suitability of the SYT2 syt2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Synaptotagmin I/II, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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