Rabbit anti-Human, Mouse CTRP6 Polyclonal Antibody | anti-C1QTNF6 antibody

CTRP6, CT (C1q Tumor Necrosis Factor alpha Related Protein 6)

Cat. Num. AAA616438

• Gene Names: C1QTNF6; CTRP6; ZACRP6
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by immunoaffinity chromatography.
• Synonyms: CTRP6; Polyclonal Antibody; CT (C1q Tumor Necrosis Factor alpha Related Protein 6); Anti -CTRP6; anti-C1QTNF6 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human CTRP6. Species Crossreactivity: mouse.
• Purity/Purification: Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.

• Applicable Applications for anti-C1QTNF6 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.; Dilution: Western Blot: 1ug'ml
• Immunogen: Synthetic peptide CTRP6 15aa near the carboxy-terminus of human CTRP6 (Genbank accession No. AAQ88740).
• Positive Control: HeLa cell lysate
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Western Blot (WB)

(Western blot analysis of CTRP6 in HeLa cell lysate with MBS616438 at (A) 1ug/ml and (B) 2ug/ml.)

Related Product Information for anti-C1QTNF6 antibody

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a
variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor- - related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of
tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). CTRP6 contains at least 4
glycosylation motifs, suggesting that CTRP6 may be highly post-translationally modified (3).

Product Categories/Family for anti-C1QTNF6 antibody

Antibodies; Abs to Growth Factors; Cytokines

NCBI and Uniprot Product Information

• NCBI GI #: 32967300
• NCBI GeneID: 114904
• NCBI Accession #: NP_872292.1
• NCBI GenBank Nucleotide #: NM_182486.1
• UniProt Accession #: Q6ICB7; Q9BXI9
• Molecular Weight: 30,962 Da
• NCBI Official Full Name: complement C1q tumor necrosis factor-related protein 6
• NCBI Official Synonym Full Names: C1q and tumor necrosis factor related protein 6
• NCBI Official Symbol: C1QTNF6
• NCBI Official Synonym Symbols: CTRP6; ZACRP6
• NCBI Protein Information: complement C1q tumor necrosis factor-related protein 6; OTTHUMP00000197772; OTTHUMP00000197774; complement-c1q tumor necrosis factor-related protein 6
• UniProt Protein Name: DJ151B14.4 protein
• Protein Family: Complement C1q tumor necrosis factor-related protein
• UniProt Gene Name: dJ151B14.4
• UniProt Entry Name: Q6ICB7_HUMAN

Uniprot Description

C1QTNF6: 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: extracellular space; collagen

Molecular Function: identical protein binding