Western Blot (WB)
(Western Blot analysis of C1QTNF5 expression in transfected 293T cell line by C1QTNF5 polyclonal antibody. Lane 1: C1QTNF5 transfected lysate (26.73kD). Lane 2: Non-transfected lysate.)
Mouse anti-Human CTRP5 Polyclonal Antibody | anti-C1QTNF5 antibody
CTRP5 (C1q and Tumor Necrosis Factor Related Protein 5, C1QTNF5, DKFZP586B0621, FLJ30570, LORD)
Gene Names
C1QTNF5; CTRP5
Reactivity
Human
Applications
Western Blot
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
CTRP5; Polyclonal Antibody; CTRP5 (C1q and Tumor Necrosis Factor Related Protein 5; C1QTNF5; DKFZP586B0621; FLJ30570; LORD); Anti -CTRP5 (C1q and Tumor Necrosis Factor Related Protein 5; anti-C1QTNF5 antibody
Host
Mouse
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human C1QTNF5.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Sequence
MRPLLVLLLLGLAAGSPPLDDNKIPSLCPGHPGLPGTPGHHGSRGLPGRDGRDGRDGAPGAPGEKGEGGRPGLPGPRGDPGPRGEAGPAGPTGPAGECSVPPRSAFSAKRSESRVPPPSDAPLPFDRVLVNEQGHYDAVTGKFTCQVPGVYYFAVHATVYRASLQFDLVKNGESIASFFQFFGGWPKPASLSGGAMVRLEPEDQVWVQVGVGDYIGIYASIKTDSTFSGFLVYSDWHSSPVFA
Applicable Applications for anti-C1QTNF5 antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Immunogen
Full length human C1QTNF5, aa1-243 (AAH29485.1).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot analysis of C1QTNF5 expression in transfected 293T cell line by C1QTNF5 polyclonal antibody. Lane 1: C1QTNF5 transfected lysate (26.73kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of C1QTNF5 expression in transfected 293T cell line by C1QTNF5 polyclonal antibody. Lane 1: C1QTNF5 transfected lysate (26.73kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-C1QTNF5 antibody
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor protein family (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. CTRP5 has been suggested to be involved in age-related macular degeneration.
Product Categories/Family for anti-C1QTNF5 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
25,298 Da
NCBI Official Full Name
complement C1q tumor necrosis factor-related protein 5
NCBI Official Synonym Full Names
C1q and tumor necrosis factor related protein 5
NCBI Official Symbol
C1QTNF5
NCBI Official Synonym Symbols
CTRP5
NCBI Protein Information
complement C1q tumor necrosis factor-related protein 5; myonectin; C1q TNF-alpha-related protein 5
UniProt Protein Name
Complement C1q tumor necrosis factor-related protein 5
Protein Family
UniProt Gene Name
C1QTNF5
UniProt Synonym Gene Names
CTRP5
UniProt Entry Name
C1QT5_HUMAN
NCBI Description
This gene encodes a member of a family of proteins that function as components of basement membranes and may play a role in cell adhesion. Mutations in this gene have been associated with late-onset retinal degeneration. The protein may be encoded by either a bicistronic transcript including sequence from the upstream membrane frizzled-related protein gene (MFRP), or by a monocistronic transcript expressed from an internal promoter. [provided by RefSeq, Jun 2013]
Uniprot Description
C1QTNF5: Defects in C1QTNF5 are a cause of late-onset retinal degeneration (LORD). LORD is an autosomal dominant disorder characterized by onset in the fifth to sixth decade with night blindness and punctate yellow-white deposits in the retinal fundus, progressing to severe central and peripheral degeneration, with choroidal neovascularization and chorioretinal atrophy.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 11q23.3
Cellular Component: collagen
Disease: Late-onset Retinal Degeneration
Research Articles on C1QTNF5
Similar Products
Product Notes
The C1QTNF5 c1qtnf5 (Catalog #AAA641199) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CTRP5 (C1q and Tumor Necrosis Factor Related Protein 5, C1QTNF5, DKFZP586B0621, FLJ30570, LORD) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CTRP5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the C1QTNF5 c1qtnf5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MRPLLVLLLL GLAAGSPPLD DNKIPSLCPG HPGLPGTPGH HGSRGLPGRD GRDGRDGAPG APGEKGEGGR PGLPGPRGDP GPRGEAGPAG PTGPAGECSV PPRSAFSAKR SESRVPPPSD APLPFDRVLV NEQGHYDAVT GKFTCQVPGV YYFAVHATVY RASLQFDLVK NGESIASFFQ FFGGWPKPAS LSGGAMVRLE PEDQVWVQVG VGDYIGIYAS IKTDSTFSGF LVYSDWHSSP VFA. It is sometimes possible for the material contained within the vial of "CTRP5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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