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Western Blot (WB) (Western blot analysis of CTRP4 in rat brain cell lysate with CTRP4 antibody at (A) 1, (B) 2, and (C) 4 μg/mL. )

Rabbit CTRP4 Polyclonal Antibody | anti-C1QTNF4 antibody

CTRP4 Antibody

Gene Names
C1QTNF4; CTRP4; ZACRP4
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
CTRP4 Antibody is affinity chromatography purified via peptide column.
Synonyms
CTRP4; Polyclonal Antibody; CTRP4 Antibody; ZACRP4; Complement C1q tumor necrosis factor-related protein 4; C1q and tumor necrosis factor related protein 4; anti-C1QTNF4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.
Purity/Purification
CTRP4 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
329
Applicable Applications for anti-C1QTNF4 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
CTRP4 antibody can be used for the detection of CTRP4 by Western blot at 1 - 4 mug/mL. Antibody can also be used for immunohistochemistry starting at 10 mug/mL. For immunofluorescence start at 20 mug/mL.
Conjugate
Unconjugated
Immunogen
CTRP4 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human CTRP4.
Buffer
CTRP4 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
CTRP4 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of CTRP4 in rat brain cell lysate with CTRP4 antibody at (A) 1, (B) 2, and (C) 4 μg/mL. )

Western Blot (WB) (Western blot analysis of CTRP4 in rat brain cell lysate with CTRP4 antibody at (A) 1, (B) 2, and (C) 4 μg/mL. )

Immunohistochemistry (IHC)

(Immunohistochemistry of CTRP4 in rat brain with CTRP4 antibody at 10 μg/mL.)

Immunohistochemistry (IHC) (Immunohistochemistry of CTRP4 in rat brain with CTRP4 antibody at 10 μg/mL.)

Immunofluorescence (IF)

(Immunofluorescence of CTRP4 in Rat Brain cells with CTRP4 antibody at 20 μg/mL.)

Immunofluorescence (IF) (Immunofluorescence of CTRP4 in Rat Brain cells with CTRP4 antibody at 20 μg/mL.)
Related Product Information for anti-C1QTNF4 antibody
CTRP4 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Multiple isoforms of mouse CTRP4 have been reported.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
35,256 Da
NCBI Official Full Name
C1q and tumor necrosis factor related protein 4
NCBI Official Synonym Full Names
C1q and tumor necrosis factor related protein 4
NCBI Official Symbol
C1QTNF4
NCBI Official Synonym Symbols
CTRP4; ZACRP4
NCBI Protein Information
complement C1q tumor necrosis factor-related protein 4; complement-c1q tumor necrosis factor-related protein 4
UniProt Protein Name
Complement C1q tumor necrosis factor-related protein 4
UniProt Gene Name
C1QTNF4
UniProt Synonym Gene Names
CTRP4
UniProt Entry Name
C1QT4_HUMAN

Uniprot Description

C1QTNF4: May act as a pro-inflammatory cytokine, that induces the activation of NF-kappa-B signaling pathway and up-regulates IL6 production. Up-regulated by IL6

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 11q11

Cellular Component: extracellular space

Molecular Function: cytokine activity

Research Articles on C1QTNF4

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Product Notes

The C1QTNF4 c1qtnf4 (Catalog #AAA150577) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CTRP4 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CTRP4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). CTRP4 antibody can be used for the detection of CTRP4 by Western blot at 1 - 4 mug/mL. Antibody can also be used for immunohistochemistry starting at 10 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the C1QTNF4 c1qtnf4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CTRP4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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