Rabbit anti-Rat HCN4 Polyclonal Antibody | anti-HCN4 antibody
HCN4 (Hyperpolarization-activated Cyclic Nucleotide-gated channel 4)
Reactivity
Rat
Applications
ELISA, Western Blot
Purity
SerumSerum
Synonyms
HCN4; Polyclonal Antibody; HCN4 (Hyperpolarization-activated Cyclic Nucleotide-gated channel 4); Anti -HCN4 (Hyperpolarization-activated Cyclic Nucleotide-gated channel 4); anti-HCN4 antibody
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes rat Hyperpolarization-activated Cyclic Nucleotide-gated channel 4. Species sequence homology: (93%) rabbit and (86%) human, primate. No significant sequence homology is seen with other HCNs or any other protein.
Purity/Purification
Serum
Serum
Serum
Form/Format
Supplied as a liquid in PBS, 0.05% sodium azide, 40% glycerol.
Applicable Applications for anti-HCN4 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1:1000-1:5000.
ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide/well.
Dilution: Western Blot: 1:1000-1:5000.
ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide/well.
Immunogen
A 15-aa peptide sequence corresponding to the cytoplasmic, C-terminus of rat HCN4 (KLH).
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-HCN4 antibody
Biological rhythms (beating of the heart, circadian sleep cycles, respiration, and the release of hormones) are necessary to sustain life. Heart beating is the most reliable and rhythmic biological phenomenon. Cardiac pacemaking is produced by the slow diastolic depolarization phase of the action potential. The hyperpolarization-activated cation current (termed If, Ih, or Iq) plays a key role in the in the initiation and modulation of cardiac and neuronal pacemaker depolarization. The generation of cardiac pacemaker potentials relies on a complex interplay between at least four different types of cation channels: T- and L-type Ca2+ channels, K+ channels, and a cation channel termed If (synonymous names are Ih and Iq). The If channel has been designated as "pacemaker" channel because it reveals unique features that are believed to be a prerequisite for pacemaker activity. Recently, the hyperpolarization-activated cyclic nucleotide-gated families of ion channel proteins (HCN1-4) have been identified as the "pacemaker" channel.
Product Categories/Family for anti-HCN4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
NCBI Official Symbol
HCN4
NCBI Protein Information
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
Similar Products
Product Notes
The HCN4 (Catalog #AAA612983) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HCN4 (Hyperpolarization-activated Cyclic Nucleotide-gated channel 4) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HCN4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: Western Blot: 1:1000-1:5000. ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide/well. Researchers should empirically determine the suitability of the HCN4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HCN4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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