Rabbit anti-Rat P2X6 Receptor Polyclonal Antibody | anti-P2RX6 antibody

P2X6 Receptor

Cat. Num. AAA612717

• Gene Names: P2RX6; P2X6; P2XM; P2RXL1; MGC129625
• Reactivity: Rat
• Applications: Western Blot
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: P2X6 Receptor; Polyclonal Antibody; Anti -P2X6 Receptor; anti-P2RX6 antibody

• Host: Rabbit
• Reactivity: Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes P2X6 Receptor. The epitope specific for the P2X6 receptor is not present in any other known proteins. Species Crossreactivity: Rat. The immunogen sequence is conserved in mouse (15/15) and human (14/17).
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a lyophilized powder. Reconstitute with 200ul of sterile distilled water.

• Applicable Applications for anti-P2RX6 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blotting.; Dilution: Western blotting: 1:200 using ECL on rat brain membranes.
• Immunogen: Highly purified peptide corresponding to residues 363-379 of rat P2X6 (Accession P51579).
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (30-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Categories/Family for anti-P2RX6 antibody

Antibodies; Abs to Receptors

NCBI and Uniprot Product Information

• NCBI GI #: 227116341
• NCBI GeneID: 9127
• NCBI Accession #: NP_001153026.1
• NCBI GenBank Nucleotide #: NM_001159554.1
• UniProt Accession #: O15547; Q58F04; Q6IC33; Q9UL50; Q05BG9; Q32MB6; Q6P1Z3
• Molecular Weight: 48,829 Da
• NCBI Official Full Name: P2X purinoceptor 6 isoform 2
• NCBI Official Synonym Full Names: purinergic receptor P2X, ligand-gated ion channel, 6
• NCBI Official Symbol: P2RX6
• NCBI Official Synonym Symbols: P2X6; P2XM; P2RXL1; MGC129625
• NCBI Protein Information: P2X purinoceptor 6; ATP receptor; purinoceptor P2X6; OTTHUMP00000198256; OTTHUMP00000198654; purinoreceptor P2X6; skeletal muscle-expressed P2X; purinergic receptor P2X-like 1, orphan receptor
• UniProt Protein Name: P2X purinoceptor 6
• Protein Family: P2X purinoceptor
• UniProt Gene Name: P2RX6
• UniProt Synonym Gene Names: P2RXL1; P2X6
• UniProt Entry Name: P2RX6_HUMAN

NCBI Description

The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified. [provided by RefSeq]

Uniprot Description

P2X6: Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.

Protein type: Channel, ligand-gated; Channel, cation; Receptor, misc.; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 22q11.21

Cellular Component: cell soma; integral to plasma membrane; postsynaptic density; cytoplasm; dendritic spine; integral to nuclear inner membrane; cell junction

Molecular Function: identical protein binding; transmembrane receptor activity; channel activity; purinergic nucleotide receptor activity; ATP binding; ATP-gated cation channel activity

Biological Process: muscle contraction; transport; protein heterooligomerization; signal transduction; transmembrane transport; protein homooligomerization; cation transport