Human anti-Human OX40L Monoclonal Antibody | anti-OX40L antibody
Human Anti-OX40L (CD252, CD134L, OX40 Ligand, TNFSF4, Tumor Necrosis Factor Superfamily Member 4, TAX Transcriptionally-activated Glycoprotein 1, TXGP1, gp34)
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Purity
Purified by Protein A affinity chromatography.
Synonyms
OX40L; Monoclonal Antibody; Human Anti-OX40L (CD252; CD134L; OX40 Ligand; TNFSF4; Tumor Necrosis Factor Superfamily Member 4; TAX Transcriptionally-activated Glycoprotein 1; TXGP1; gp34); anti-OX40L antibody
Host
Human
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
R4930
Specificity
Recognizes human OX40L.
Purity/Purification
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS. No preservative added.
Applicable Applications for anti-OX40L antibody
Flow Cytometry (FC/FACS)
Application Notes
Flow Cytometry: 1ug/ml Blocking: Binds to the co-stimulatory human OX40L inhibiting its interaction with OX40 in vitro and in vivo. Optimal dilutions to be determined by the researcher.
Endotoxin
<0.001EU/ug
Immunogen
Recombinant protein corresponding to human OX40L expressed in CHO cells.
Note
Preservative Free
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-OX40L antibody
OX40L [CD252; CD134L] is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium.
References
1. In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation: D. Se- shasayee, et al.; J. Clin. Invest. 117, 3868 (2007). 2. Monoclonal antibodies for the treatment of asthma: M.C. Catley, et al.; Pharm. Ther. 132, 333 (2011). 3. OX40L blockade and allergen-induced airway responses in subjects with mild asthma: G.M. Gauvreau, et al.; Clin. Exp. Allergy 44, 29 (2014).
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Product Notes
The OX40L (Catalog #AAA6120625) is an Antibody produced from Human and is intended for research purposes only. The product is available for immediate purchase. The Human Anti-OX40L (CD252, CD134L, OX40 Ligand, TNFSF4, Tumor Necrosis Factor Superfamily Member 4, TAX Transcriptionally-activated Glycoprotein 1, TXGP1, gp34) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's OX40L can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Flow Cytometry: 1ug/ml Blocking: Binds to the co-stimulatory human OX40L inhibiting its interaction with OX40 in vitro and in vivo. Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the OX40L for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OX40L, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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