Rabbit Conalbumin, Chicken Polyclonal Antibody | anti-TF antibody
Conalbumin, Chicken
Gene Names
TF; LTF; TFEW; conalbumin
Reactivity
Chicken
Applications
ELISA, Western Blot
Purity
Serum
Synonyms
Conalbumin; Chicken; Polyclonal Antibody; Anti -Conalbumin; anti-TF antibody
Host
Rabbit
Reactivity
Chicken
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes chicken Conalbumin protein.
Purity/Purification
Serum
Form/Format
Supplied as a lyophilized powder from PBS, 0.05% sodium azide. Reconstitute with 100ul sterile PBS.
Applicable Applications for anti-TF antibody
ELISA (EL/EIA), Western Blot (WB). Other applications not tested.
Application Notes
Suitable for use in Western Blot and ELISA.
Dilution: ELISA: 1:10,000-1:50,000
Western Blot: 1:1000-1:5000 (ECL).
Optimal dilutions to be determined by the researcher.
Dilution: ELISA: 1:10,000-1:50,000
Western Blot: 1:1000-1:5000 (ECL).
Optimal dilutions to be determined by the researcher.
Control No.
C15012164
Revision No.
051713
Immunogen
Highly purified chicken egg white conalbumin (705aa).
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-TF antibody
Allergy to chicken egg or proteins is one of the more frequent causes of food hypersensitivity in infants and young children. Both IgG and IgA class antibodies may be detected. Ovalbumin intolerance has been implicated in a number of conditions affecting children. In particular, children with cystic fibrosis show elevated anti-ovalbumin antibodies. Ovalbumin antibodies have also been noted in some forms of kidney disease. A relationship between food allergy and infantile autism has also been observed. Children with insulin dependent diabetes mellitus show an enhanced immune response to both b-lactoglobulin and ovalbumin, a phenomenon that may be related to the development of the disease. Intolerance to egg proteins could be due not only to the ovalbumin protein found in egg white but also to other major proteins present in the yolk. The major proteins of chicken eggs are: Ovalbumin (54%), Conalbumin (13%), Ovomucoid(11%), Lysozyme (3.5%), Globulins (G2, G3) (8.0%), Ovomucin (1.5%). Conalbumin or transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Transferrin has a bacteriostatic function. Its concentration in avian egg is the highest concentration of any transferrin in vivo. Transferrin in liver is regulated by the iron levels but not in the oviduct. These two forms of transferrin (liver and oviduct) differ only by their carbohydrate composition.
Product Categories/Family for anti-TF antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
77,777 Da
NCBI Official Full Name
conalbumin
NCBI Official Symbol
TF
NCBI Official Synonym Symbols
LTF; TFEW; conalbumin
NCBI Protein Information
ovotransferrin; lactotransferrin; serum transferrin; allergen Gal d III; ovotransferrin BB type; ovotransferrin BC type; ovotransferrin CC type
UniProt Protein Name
Ovotransferrin
UniProt Entry Name
TRFE_CHICK
Uniprot Description
Function: Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.Transferrin has a bacteriostatic function. Its concentration in avian egg is the highest concentration of any transferrin in vivo. Transferrin in liver is regulated by the iron levels but not in the oviduct. These two forms of transferrin (liver and oviduct) differ only by their carbohydrate composition.
Subunit structure: Monomer.
Subcellular location: Secreted.
Allergenic properties: Causes an allergic reaction in human.
Sequence similarities: Belongs to the transferrin family.Contains 2 transferrin-like domains.
Research Articles on TF
1. Several proteins associated with the egg shell membranes (ESM) with antibacterial activity have been identified including ovotransferrin, in addition, pure fractions of ovotransferrin were obtained from egg white.
2. Ovotransferrin is able to cleave itself through the unique chemical reactivity of four tripeptides motifs, HTT (residues 209-211), HST (residues 542-544) and two CHT (residues 115-117 and 454-456).
3. Marked stabilization effects by amino(N)- and carboxyl(C)-terminal lobes of ovotransferrin are induced during iron binding, primarily upon N-lobe iron binding in the iron-free C-lobe and secondarily upon C-lobe iron binding in the monoferric N-lobe.
2. Ovotransferrin is able to cleave itself through the unique chemical reactivity of four tripeptides motifs, HTT (residues 209-211), HST (residues 542-544) and two CHT (residues 115-117 and 454-456).
3. Marked stabilization effects by amino(N)- and carboxyl(C)-terminal lobes of ovotransferrin are induced during iron binding, primarily upon N-lobe iron binding in the iron-free C-lobe and secondarily upon C-lobe iron binding in the monoferric N-lobe.
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Product Notes
The TF (Catalog #AAA611114) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Conalbumin, Chicken reacts with Chicken and may cross-react with other species as described in the data sheet. AAA Biotech's Conalbumin, Chicken can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Other applications not tested. Suitable for use in Western Blot and ELISA. Dilution: ELISA: 1:10,000-1:50,000 Western Blot: 1:1000-1:5000 (ECL). Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the TF for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Conalbumin, Chicken, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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