Ovotransferrin Native Protein | LTF native protein

Chicken Ovotransferrin

Cat. Num. AAA717021

• Gene Names: LTF; TF; TFEW; conalbumin
• Applications: ELISA
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Ovotransferrin; Chicken Ovotransferrin; Allergen Gal d III; Conalbumin; Serum transferrin; LTF native protein

• Host: Purified from chicken egg white
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Liquid

• Applicable Applications for LTF native protein: Western blotting,ELISA,etc.
• Peptide: Full length native Chicken Ovotransferrin
• Storage Buffer: 20mM Tris, pH8.0,50%glycerol
• Preparation and Storage: Aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze / thaw cycles.

SDS-PAGE

Related Product Information for LTF native protein

Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. Transferrin has a bacteriostatic function. Its concentration in avian egg is the highest concentration of any transferrin in vivo. Transferrin in liver is regulated by the iron levels but not in the oviduct. These two forms of transferrin (liver and oviduct) differ only by their carbohydrate composition.

NCBI and Uniprot Product Information

• NCBI GI #: 45385813
• NCBI GeneID: 396241
• NCBI Accession #: NP_990635.1
• NCBI GenBank Nucleotide #: NM_205304.1
• UniProt Accession #: P02789
• NCBI Official Full Name: ovotransferrin
• NCBI Official Synonym Full Names: lactotransferrin
• NCBI Official Symbol: LTF
• NCBI Official Synonym Symbols: TF; TFEW; conalbumin
• NCBI Protein Information: ovotransferrin; serum transferrin; allergen Gal d III; ovotransferrin BB type; ovotransferrin BC type; ovotransferrin CC type
• UniProt Protein Name: Ovotransferrin
• Protein Family: Ovotransferrin
• UniProt Entry Name: TRFE_CHICK

Uniprot Description

Function: Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. Responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. There are two forms of hen transferrin, ovotransferrin, found in the ovoducts and, serum transferrin, secreted by the liver. Serum transferrin may also have a role in stimulating cell proliferation and is regulated by iron levels. Ovotransferrin has a bacteriostatic function and, is not controlled by iron levels.

Subunit structure: Monomer.

Subcellular location: Secreted.

Post-translational modification: Different forms of hen transferrin are distinguished by their carbohydrate composition. Ovotransferrin and embryo serum transferrin but not adult serum transferrin, have bisecting N-acetylglucosamine. Transferrin secreted by embryo hepatocytes in primary culture is marked by the presence of (alpha1-6) fucosylation of the core N-acetylglucosamine. Serum transferrins also differ in the number of attached neuraminic acid residues. In both embryo forms, sialylation occurs on the Man (alpha 1-3)-linked antennae.

Allergenic properties: Causes an allergic reaction in human.

Sequence similarities: Belongs to the transferrin family.Contains 2 transferrin-like domains.