Mouse anti-Human, Rat MSRA Monoclonal Antibody | anti-msrA antibody
MSRA (Methionine Sulfoxide Reductase A, Peptide Methionine Sulfoxide Reductase, Peptide-methionine (S)-S-oxide Reductase, Peptide Met(O) Reductase, Protein-methionine-S-oxide Reductase, PMSR)
Reactivity
Human, Rat
Applications
Immunoprecipitation, Immunohistochemistry
Purity
AscitesAscites
Synonyms
MSRA; Monoclonal Antibody; MSRA (Methionine Sulfoxide Reductase A; Peptide Methionine Sulfoxide Reductase; Peptide-methionine (S)-S-oxide Reductase; Peptide Met(O) Reductase; Protein-methionine-S-oxide Reductase; PMSR); Anti -MSRA (Methionine Sulfoxide Reductase A; anti-msrA antibody
Host
Mouse
Reactivity
Human, Rat
Clonality
Monoclonal
Isotype
IgG2b, k
Clone Number
10K277
Specificity
Recognizes human Methionine Sulfoxide Reductase A. Species crossreactivity: rat.
Purity/Purification
Ascites
Ascites
Ascites
Form/Format
Supplied as a liquid in PBS, 50% glycerol.
Applicable Applications for anti-msrA antibody
Immunoprecipitation (IP), Immunohistochemistry (IHC)
Application Notes
Suitable for use in Immunohistochemistry and Immunoprecipitation.
Dilution: Immunoprecipitation: 1-2ul/400ul lysates
Dilution: Immunoprecipitation: 1-2ul/400ul lysates
Immunogen
Recombinant human protein purified from E.coli.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at -70 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months.
Related Product Information for anti-msrA antibody
Methionine sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to Methionine (Met). The catalytic activity of MsrA is dependent of bound metal and cofactors but it requires reducing equivalents from either DTT or a thioredoxin-regenerating system. MsrA plays an essential role in protecting cells against oxidative damage. The substrates of MsrA include calmodulin, HIV protease and 1-proteinase-inhibitor. Recent studies indicate that there is a connection between MsrA and Alzheimer's disease in mammals.
Product Categories/Family for anti-msrA antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
19,621 Da
NCBI Official Full Name
MsrA
NCBI Official Symbol
msrA
NCBI Protein Information
ORF20; MsrA
UniProt Protein Name
Peptide methionine sulfoxide reductase MsrA
Protein Family
UniProt Gene Name
msrA
UniProt Entry Name
Q7X3U7_9ENTR
Uniprot Description
Function: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
By similarity. HAMAP MF_01401
Catalytic activity: L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 SAAS SAAS002569
Sequence similarities: Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401
Similar Products
Product Notes
The msrA msra (Catalog #AAA609131) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MSRA (Methionine Sulfoxide Reductase A, Peptide Methionine Sulfoxide Reductase, Peptide-methionine (S)-S-oxide Reductase, Peptide Met(O) Reductase, Protein-methionine-S-oxide Reductase, PMSR) reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MSRA can be used in a range of immunoassay formats including, but not limited to, Immunoprecipitation (IP), Immunohistochemistry (IHC). Suitable for use in Immunohistochemistry and Immunoprecipitation. Dilution: Immunoprecipitation: 1-2ul/400ul lysates. Researchers should empirically determine the suitability of the msrA msra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MSRA, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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