Rabbit anti-Human PP6R3 Polyclonal Antibody | anti-PPP6R3 antibody
PP6R3 (Serine/Threonine-protein Phosphatase 6 Regulatory Subunit 3, SAPS Domain Family Member 3, Sporulation-induced Transcript 4-associated Protein SAPL, PPP6R3, C11orf23, KIAA1558, SAPL, SAPS3)
Gene Names
PPP6R3; SAPL; PP6R3; SAPLa; SAPS3; SAP190; C11orf23
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
PP6R3; Polyclonal Antibody; PP6R3 (Serine/Threonine-protein Phosphatase 6 Regulatory Subunit 3; SAPS Domain Family Member 3; Sporulation-induced Transcript 4-associated Protein SAPL; PPP6R3; C11orf23; KIAA1558; SAPL; SAPS3); Anti -PP6R3 (Serine/Threonine-protein Phosphatase 6 Regulatory Subunit 3; anti-PPP6R3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Recognizes human PP6R3.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
Applicable Applications for anti-PPP6R3 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Western Blot: 1:10,000
Immunohistochemistry: 1:200
Dilution: Western Blot: 1:10,000
Immunohistochemistry: 1:200
Immunogen
Recombinant corresponding to human PP6R3 fused to His-tag.
Positive Control
HeLa cell lysate
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-PPP6R3 antibody
PP6R3 also known as SAPS3 is a regulatory subunit of protein phosphatase 6 which is important for cell survival and is associated with TOR signaling in yeast. PP6R3 has been implicated in the transition from G1 to the S phase of mitosis. The PP6R3 subunit is one of three human versions of SAPs which may also have a role to play in regulation of NF-kappaB.
Product Categories/Family for anti-PPP6R3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
97,669 Da
NCBI Official Full Name
serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X5
NCBI Official Synonym Full Names
protein phosphatase 6, regulatory subunit 3
NCBI Official Symbol
PPP6R3
NCBI Official Synonym Symbols
SAPL; PP6R3; SAPLa; SAPS3; SAP190; C11orf23
NCBI Protein Information
serine/threonine-protein phosphatase 6 regulatory subunit 3; SAPS domain family, member 3; sporulation-induced transcript 4-associated protein SAPL
UniProt Protein Name
Serine/threonine-protein phosphatase 6 regulatory subunit 3
Protein Family
UniProt Gene Name
PPP6R3
UniProt Synonym Gene Names
C11orf23; KIAA1558; PP6R3; SAPL; SAPS3
UniProt Entry Name
PP6R3_HUMAN
NCBI Description
Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010]
Uniprot Description
SAPLa: Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. May have an important role in maintaining immune self-tolerance. Belongs to the SAPS family. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 11q13
Cellular Component: nucleoplasm; cytoplasm; plasma membrane
Molecular Function: protein binding; protein phosphatase binding
Biological Process: regulation of phosphoprotein phosphatase activity
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Product Notes
The PPP6R3 ppp6r3 (Catalog #AAA6012128) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PP6R3 (Serine/Threonine-protein Phosphatase 6 Regulatory Subunit 3, SAPS Domain Family Member 3, Sporulation-induced Transcript 4-associated Protein SAPL, PPP6R3, C11orf23, KIAA1558, SAPL, SAPS3) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PP6R3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Western Blot and Immunohistochemistry. Dilution: Western Blot: 1:10,000 Immunohistochemistry: 1:200. Researchers should empirically determine the suitability of the PPP6R3 ppp6r3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PP6R3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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