Rat anti-Human, Mouse Nectin-2 Monoclonal Antibody | anti-PVRL2 antibody
Nectin-2 (Poliovirus Receptor-related Protein 2, Herpes Virus Entry Mediator B, Herpesvirus Entry Mediator B, HveB, Murine Herpes Virus Entry Protein B, mHveB, Poliovirus Receptor Homolog, CD112, Pvrl2, Mph, Pvr, Pvs) (FITC)
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
Affinity PurifiedPurified by Protein G affinity chromatography.
Synonyms
Nectin-2; Monoclonal Antibody; Nectin-2 (Poliovirus Receptor-related Protein 2; Herpes Virus Entry Mediator B; Herpesvirus Entry Mediator B; HveB; Murine Herpes Virus Entry Protein B; mHveB; Poliovirus Receptor Homolog; CD112; Pvrl2; Mph; Pvr; Pvs) (FITC); Anti -Nectin-2 (Poliovirus Receptor-related Protein 2; anti-PVRL2 antibody
Host
Rat
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
13A61
Specificity
Recognizes mouse Nectin-2. Species Crossreactivity: human.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
Applicable Applications for anti-PVRL2 antibody
ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes
Suitable for use in Flow Cytometry, ELISA, Western Blot, Immunoprecipitation and Immunohistochemistry.
Dilution: Immunohistochemistry: Frozen (PFA or acetone/methanol fixation)
Flow Cytometry: 1:10
Western Blot: 1:10
Dilution: Immunohistochemistry: Frozen (PFA or acetone/methanol fixation)
Flow Cytometry: 1:10
Western Blot: 1:10
Immunogen
Extracellular domain of mouse nectin-2
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light.
Related Product Information for anti-PVRL2 antibody
Nectin (originally isolated as poliovirus receptor-related protein (PRR)) is a cell-cell adhesion molecule of the immunoglobulin supergene family. Nectin is colocalized with afadin at cadherin-based cell-cell adherence junctions in various tissues and cell lines. The nectin family consist of nectin-1, nectin-2 and nectin-3. Nectin-2 also known as PRR2 or CD112 is a plasma membrane adhesion molecule localized at adherens junctions which is widely expressed in various cell lines including neuronal, endothelial, epithelial and hematopoietic cells. Next to its role in adherens junctions it functions as alphaherpus virus receptor and acts also as intercellular adhesion molecule and pseudorabies virus receptor. Disruption of mouse nectin-2 leads to infertility of male mice.
Product Categories/Family for anti-PVRL2 antibody
NCBI and Uniprot Product Information
Similar Products
Product Notes
The PVRL2 (Catalog #AAA6011063) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Nectin-2 (Poliovirus Receptor-related Protein 2, Herpes Virus Entry Mediator B, Herpesvirus Entry Mediator B, HveB, Murine Herpes Virus Entry Protein B, mHveB, Poliovirus Receptor Homolog, CD112, Pvrl2, Mph, Pvr, Pvs) (FITC) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Nectin-2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). Suitable for use in Flow Cytometry, ELISA, Western Blot, Immunoprecipitation and Immunohistochemistry. Dilution: Immunohistochemistry: Frozen (PFA or acetone/methanol fixation) Flow Cytometry: 1:10 Western Blot: 1:10. Researchers should empirically determine the suitability of the PVRL2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Nectin-2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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