Mouse anti-Human alpha1-antitrypsin Monoclonal Antibody
mAb anti-Human alpha1-antitrypsin
Reactivity
Human
Applications
Western Blot
Purity
Protein G affinity purified
Synonyms
alpha1-antitrypsin; Monoclonal Antibody; mAb anti-Human alpha1-antitrypsin; Alpha 1-Antitrypsin; Mouse monoclonal antibody to human alpha1-antitrypsin; anti-alpha1-antitrypsin antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
5G5
Specificity
This monoclonal antibody reacts with human alpha1-antitrypsin
Purity/Purification
Protein G affinity purified
Form/Format
Lyophilized from a solution in 0.01M PBS, pH 7.2
Sequence Length
409
Applicable Applications for anti-alpha1-antitrypsin antibody
Western Blot (WB)
Application Notes
Western Blot: Detect alpha1-antitrypsin (alpha1 AAT) using antibody 5G5 at 1:5000 dilution (0.2 mug/mL).
Target Protein
Human alpha1-antitrypsin
Immunogen
Human plasma derived alpha1-antitrypsin
Myeloma
Sp2/0-Ag14
Light Chain
Kappa
Reconstitution
Double distilled water is recommended to adjust the final concentration to 1.00 mg/mL.
Research Area
alpha1-antitrypsin deficiency disorder, Alzheimer's disease
Preparation and Storage
Store at -20 degree C
Related Product Information for anti-alpha1-antitrypsin antibody
Description: Mouse monoclonal antibody to human alpha1-antitrypsin
background: alpha1-antitrypsin is a protective protease inhibitor. It inhibits elastase released by neutrolphils during inflammatory reaction and irreversibly inactivates trypsin secreted in duodenum and else where. alpha1-antitrypsin normally presents in plasma at 1.5-3.5 mg/mL, but increases in acute phase reaction, malignancies, pregnancy and trauma. Severe hereditary alpha1-antitrypsin deficiency can result in damages to alveoli, chronic obstructive pulmonary disease (COPD), and liver diseases such as jaundice and cirrhosis. The protein is also found in the neurofibrillary tangles and senile plaques in the brain lesions of Alzheimer's disease. Whether or not it contributes to the pathology of Alzheimer's disease is not confirmed.
background: alpha1-antitrypsin is a protective protease inhibitor. It inhibits elastase released by neutrolphils during inflammatory reaction and irreversibly inactivates trypsin secreted in duodenum and else where. alpha1-antitrypsin normally presents in plasma at 1.5-3.5 mg/mL, but increases in acute phase reaction, malignancies, pregnancy and trauma. Severe hereditary alpha1-antitrypsin deficiency can result in damages to alveoli, chronic obstructive pulmonary disease (COPD), and liver diseases such as jaundice and cirrhosis. The protein is also found in the neurofibrillary tangles and senile plaques in the brain lesions of Alzheimer's disease. Whether or not it contributes to the pathology of Alzheimer's disease is not confirmed.
Product Categories/Family for anti-alpha1-antitrypsin antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
alpha1 antitrypsin
Similar Products
Product Notes
The alpha1-antitrypsin (Catalog #AAA592340) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The mAb anti-Human alpha1-antitrypsin reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's alpha1-antitrypsin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: Detect alpha1-antitrypsin (alpha1 AAT) using antibody 5G5 at 1:5000 dilution (0.2 mug/mL). Researchers should empirically determine the suitability of the alpha1-antitrypsin for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "alpha1-antitrypsin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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