CD30 recombinant protein
CD30 (human):Fc (human), (recombinant)
Gene Names
TNFRSF8; CD30; Ki-1; D1S166E
Applications
ELISA
Purity
>=95% (SDS-PAGE)
Synonyms
CD30; CD30 (human):Fc (human); (recombinant); CD30 recombinant protein
Host
HEK293 cells
Specificity
Binds human CD30L (CD153)
Purity/Purification
>=95% (SDS-PAGE)
Form/Format
Lyophilized. Contains PBS
Concentration
1mg/ml after reconstitution (varies by lot)
Applicable Applications for CD30 recombinant protein
ELISA (EIA)
Source Note
The cysteine-rich region of human CD30 (Ki-1) (aa 1-380) is fused to the Fc portion of human IgG1
Endotoxin
<0.1EU/ug purified protein (LAL test)
Reconstitution
Reconstitute with 50ul sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein
Preparation and Storage
Stable for at least 6 months after receipt when stored at -20 degree C
Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20 degree C
Shipping: Shipped on Blue Ice
Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20 degree C
Shipping: Shipped on Blue Ice
Related Product Information for CD30 recombinant protein
The CD30 receptor (CD30, Ki-1) is a member of the tumor necrosis factor receptor (TNF-R) family. CD30 is a type I transmembrane receptor, it contains 6 extracellular cysteine-rich motifs, is shed by the TNFalpha-converting enzyme and is associated with the Reed-Sternberg cells of Hodgkins disease as well as with T cells and some lymphomas. Activated CD30 recruits TNF receptor-associated factor 1, 2, 3 and 5. CD30-CD30L have been reported to be involved in costimulation of T cell proliferation, induction of HIV expression, negative selection and apoptosis as well as in diabetes and several allergic, viral and autoimmune diseases.
Product Categories/Family for CD30 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
50,935 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 8 isoform 1
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily member 8
NCBI Official Symbol
TNFRSF8
NCBI Official Synonym Symbols
CD30; Ki-1; D1S166E
NCBI Protein Information
tumor necrosis factor receptor superfamily member 8
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 8
Protein Family
UniProt Gene Name
TNFRSF8
UniProt Synonym Gene Names
CD30; D1S166E
UniProt Entry Name
TNR8_HUMAN
Uniprot Description
TNFRSF8: Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF- kappa-B. 2 isoforms of the human protein are produced by alternative initiation.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 1p36
Cellular Component: integral to plasma membrane
Molecular Function: transmembrane receptor activity; tumor necrosis factor receptor activity
Biological Process: immune response; inflammatory response; multicellular organismal development; negative regulation of cell proliferation; positive regulation of apoptosis; positive regulation of TRAIL biosynthetic process; positive regulation of tumor necrosis factor biosynthetic process; response to lipopolysaccharide; signal transduction
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Product Notes
The CD30 tnfrsf8 (Catalog #AAA566209) is a Recombinant Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD30 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the CD30 tnfrsf8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD30, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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