CD31 (PECAM1) Recombinant Protein | CD31 recombinant protein

Mouse CD31 Recombinant (PECAM1)

Cat. Num. AAA553245

• Purity: >95%, as determined by SDS-PAGE and HPLC
• Synonyms: CD31 (PECAM1); Mouse CD31 Recombinant (PECAM1); Mouse CD31 Recombinant (PECAM1) ; cd31; cd-31; pecam; CD31 recombinant protein

• Host: HEk293 Cells
• Purity/Purification: >95%, as determined by SDS-PAGE and HPLC
• Form/Format: Recombinant mouse CD31 is supplied as a 0.2 um filtered PBS solution, pH7.2.
• Sequence Length: 738

• Domain: Ig-like C2
• Host Note: Optimized DNA sequence encoding extracellular domain of mouse CD31 including a C-terminal 6His tag was expressed in HEK293 cells.
• Endotoxin: Endotoxin content was assayed using a LAL gel clot method.; Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).
• Molecular Weight Note: Recombinant mouse CD31 (PECAM-1) is a monomer protein consisting of 585 amino acid residue subunits, due to glycosylation migrates as an approximately 100 kDa protein on SDS-PAGE.
• Preparation and Storage: Recombinant mouse CD31, as supplied, can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C to -70 degree C for twelve months.; ; Avoid repeated freeze/thaw cycles.

Related Product Information for CD31 recombinant protein

Platelet/endothelial cell adhesion molecule 1, also known as CD31, is a member of the Ig gene superfamily expressed at high density at the lateral borders of endothelial cells and at a lower density on the surface of hematopoietic cells including T lymphocytes. By establishing homophilic interactions between endothelium- and leukocyte- expressed CD31, this molecule has been shown to facilitate leukocyte transendothelial migration (TEM) in vitro and in vivo.

Product Categories/Family for CD31 recombinant protein

Receptors CD

References

• cd38/CD31, the ccl3 and ccl4 chemokines, and cd49d/vascular cell adhesion molecule-1 are interchained by sequential events sustaining chronic lymphocytic leukemia cell survival .Cancer Res., May 2009; 69: 4001 - 4009.
• circulating monocytes expressing CD31: implications for acute and chronic angiogenesis .Am. J. Pathol., May 2009; 174: 1972 - 1980.
• il-7 sustains CD31 expression in human naive cd4+ t cells and preferentially expands the CD31+ subset in a pi3k-dependent manner .Blood, Mar 2009; 113: 2999 - 3007.
• transcriptional profiling of CD31+ cells isolated from murine embryonic stem cells .Genes Cells, Feb 2009; 14: 243 - 260.
• life after the thymus: CD31+ and CD31– human naive cd4+ t-cell subsets .Blood, Jan 2009; 113: 769 - 774.