Western Blot (WB)
(Sample Data: Representative Western blot with Anti-PYK2 (1:1000) using 2ng of His-tagged human recombinant PYK2.)
Rabbit PYK2 Polyclonal Antibody | anti-PYK2 antibody
Anti-PYK2
Reactivity
Western blot human PYK2PYK2 from other species may also be detectable.
Applications
Western Blot
Purity
Affinity Chromatography
Synonyms
PYK2; Polyclonal Antibody; Anti-PYK2; anti-PYK2 antibody
Host
Rabbit
Reactivity
Western blot human PYK2
PYK2 from other species may also be detectable.
PYK2 from other species may also be detectable.
Clonality
Polyclonal
Specificity
Recognizes the PYK2 (FAK2) protein
Purity/Purification
Affinity Chromatography
Form/Format
PBS, pH7.4, 0.02%NaN3, 50% glycerol
Applicable Applications for anti-PYK2 antibody
Western Blot (WB)
Application Notes
WB: 18887:19886
Immunogen
Synthetic peptide corresponding to amino acids 420-424 of human PYK2
Preparation and Storage
Store at 4 degree C (add 0.1% NaN3) for several months, and at -20 degree C for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For optimal performance, avoid repeated handling and multiple freeze/thaw cycles.
Western Blot (WB)
(Sample Data: Representative Western blot with Anti-PYK2 (1:1000) using 2ng of His-tagged human recombinant PYK2.)
Western Blot (WB)
(Sample Data: Representative Western blot with Anti-PYK2 (1:1000) using 2ng of His-tagged human recombinant PYK2.)
Western Blot (WB)
(Sample Data: Representative Western blot with Anti-PYK2 (1:1000) using 20 ug, 40 ug and 65 ug of Jurkat cell lysate.)
Western Blot (WB)
(Sample Data: Representative Western blot with Anti-PYK2 (1:1000) using 20 ug, 40 ug and 65 ug of Jurkat cell lysate.)
Related Product Information for anti-PYK2 antibody
PYK2 (also known as FAK2/RAFTK) is a member of the focal adhesion PTK family. PYK2/FAK2 can be activated by a variety of extracellular signals that elevate intracellular calcium concentration, and by stress signals (1). Unlike FAK, which is widely expressed in various tissues and links transmembrane integrin receptors to intracellular pathways, PYK2/FAK2 is expressed mainly in the central nervous system and in cells derived from hematopoietic lineages. In osteoclasts, although FAK is expressed, PYK2/FAK2 appears to be the predominant mediator of integrin alpha(v)beta3 signaling events that influence osteoclast physiology and pathology (2).
Product Categories/Family for anti-PYK2 antibody
References
1. Avraham, H. et al: RAFTK/Pyk2-mediated cellular signalling. Cell Signal. 2000 Mar;12(3):123-33.
2. Xiong, W C. et al: PYK2 and FAK in osteoclasts. Front Biosci. 2003 Sep 1;8:d1219-26.
2. Xiong, W C. et al: PYK2 and FAK in osteoclasts. Front Biosci. 2003 Sep 1;8:d1219-26.
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Product Notes
The PYK2 (Catalog #AAA516170) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PYK2 reacts with Western blot human PYK2 PYK2 from other species may also be detectable. and may cross-react with other species as described in the data sheet. AAA Biotech's PYK2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 18887:19886. Researchers should empirically determine the suitability of the PYK2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PYK2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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