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Western Blot (WB) (Western Blot analysis of SENP7 in A172 and 231 cells in order using SENP7 Rabbit pAb at dilution 1/800)

Rabbit SENP7 Polyclonal Antibody | anti-SENP7 antibody

SENP7 Rabbit pAb

Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Affinity purified
Synonyms
SENP7; Polyclonal Antibody; SENP7 Rabbit pAb; SUMO1/sentrin specific peptidase 7; anti-SENP7 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.5mg/ml (varies by lot)
Applicable Applications for anti-SENP7 antibody
Western Blot (WB)
Application Notes
WB: 1:1000-1:5000
Immunogen
Fusion protein of human SENP7
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western Blot analysis of SENP7 in A172 and 231 cells in order using SENP7 Rabbit pAb at dilution 1/800)

Western Blot (WB) (Western Blot analysis of SENP7 in A172 and 231 cells in order using SENP7 Rabbit pAb at dilution 1/800)
Related Product Information for anti-SENP7 antibody
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
119,658 Da
NCBI Official Full Name
sentrin-specific protease 7 isoform 2
NCBI Official Synonym Full Names
SUMO1/sentrin specific peptidase 7
NCBI Official Symbol
SENP7
NCBI Protein Information
sentrin-specific protease 7; SUMO-1-specific protease 2; SUMO1/sentrin specific protease 7; sentrin/SUMO-specific protease SENP7
UniProt Protein Name
Sentrin-specific protease 7
Protein Family
UniProt Gene Name
SENP7
UniProt Synonym Gene Names
KIAA1707; SSP2; SUSP2
UniProt Entry Name
SENP7_HUMAN

NCBI Description

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009]

Uniprot Description

SENP7: Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full- length SUMO proteins to their mature forms. Belongs to the peptidase C48 family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.22.68; Protease

Chromosomal Location of Human Ortholog: 3q12

Cellular Component: intracellular; nucleus

Molecular Function: protein binding; cysteine-type peptidase activity

Biological Process: proteolysis

Research Articles on SENP7

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Product Notes

The SENP7 senp7 (Catalog #AAA4760146) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SENP7 Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SENP7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1000-1:5000. Researchers should empirically determine the suitability of the SENP7 senp7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SENP7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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