TIM50 Blocking Peptide | TIMM50 blocking peptide

TIM50 Immunizing Peptide

Cat. Num. AAA425520

• Gene Names: TIMM50; TIM50; TIM50L
• Reactivity: Human, Mouse, Rat, Dog, Cow
• Synonyms: TIM50; TIM50 Immunizing Peptide; TIMM50; TIM50L; translocase of inner mitochondrial membrane 50 homolog (yeast); Tim50-like protein; homolog of yeast Tim50; translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae); MGC102733; TIMM50 blocking peptide

• Reactivity: Human, Mouse, Rat, Dog, Cow
• Form/Format: 100ug of dried peptide
• Sequence: CDVRTVLEHYALEDD
• Sequence Length: 456

• Preparation and Storage: Shipped at ambient temperature, store at -20 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 48526509
• NCBI GeneID: 92609
• NCBI Accession #: NP_001001563.1
• NCBI GenBank Nucleotide #: NM_001001563.2
• Molecular Weight: 27,579 Da
• NCBI Official Full Name: mitochondrial import inner membrane translocase subunit TIM50
• NCBI Official Synonym Full Names: translocase of inner mitochondrial membrane 50
• NCBI Official Symbol: TIMM50
• NCBI Official Synonym Symbols: TIM50; TIM50L
• NCBI Protein Information: mitochondrial import inner membrane translocase subunit TIM50
• UniProt Protein Name: Mitochondrial import inner membrane translocase subunit TIM50
• Protein Family: Mitochondrial import inner membrane translocase
• UniProt Gene Name: TIMM50
• UniProt Synonym Gene Names: TIM50
• UniProt Entry Name: TIM50_HUMAN

Uniprot Description

TIMM50: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. Isoform 2 may participate in the release of snRNPs and SMN from the Cajal body. Belongs to the TIM50 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Protein phosphatase, dual-specificity; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: integral to membrane; mitochondrial inner membrane; mitochondrial inner membrane presequence translocase complex; mitochondrion; nuclear speck; nucleoplasm

Molecular Function: interleukin-2 receptor binding; phosphoprotein phosphatase activity; protein binding; protein serine/threonine phosphatase activity; protein tyrosine phosphatase activity; ribonucleoprotein binding; RNA binding

Biological Process: mitochondrial membrane organization and biogenesis; protein amino acid dephosphorylation; protein import into mitochondrial matrix; release of cytochrome c from mitochondria